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A somatic mutation of the KEAP1 gene in malignant melanoma is involved in aberrant NRF2 activation and an increase in intrinsic drug resistance.
Miura S, Shibazaki M, Kasai S, Yasuhira S, Watanabe A, Inoue T, Kageshita Y, Tsunoda K, Takahashi K, Akasaka T, Masuda T, Maesawa C. Miura S, et al. Among authors: shibazaki m. J Invest Dermatol. 2014 Feb;134(2):553-556. doi: 10.1038/jid.2013.343. Epub 2013 Aug 12. J Invest Dermatol. 2014. PMID: 23938463 Free article. No abstract available.
87 results