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DNA damage and its links to neurodegeneration.
Madabhushi R, Pan L, Tsai LH. Madabhushi R, et al. Neuron. 2014 Jul 16;83(2):266-282. doi: 10.1016/j.neuron.2014.06.034. Neuron. 2014. PMID: 25033177 Free PMC article. Review.
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes.
Madabhushi R, Gao F, Pfenning AR, Pan L, Yamakawa S, Seo J, Rueda R, Phan TX, Yamakawa H, Pao PC, Stott RT, Gjoneska E, Nott A, Cho S, Kellis M, Tsai LH. Madabhushi R, et al. Cell. 2015 Jun 18;161(7):1592-605. doi: 10.1016/j.cell.2015.05.032. Epub 2015 Jun 4. Cell. 2015. PMID: 26052046 Free PMC article.
Cortical neurons gradually attain a post-mitotic state.
Anda FC, Madabhushi R, Rei D, Meng J, Gräff J, Durak O, Meletis K, Richter M, Schwanke B, Mungenast A, Tsai LH. Anda FC, et al. Among authors: madabhushi r. Cell Res. 2016 Sep;26(9):1033-47. doi: 10.1038/cr.2016.76. Epub 2016 Jun 21. Cell Res. 2016. PMID: 27325298 Free PMC article.
Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks.
Delint-Ramirez I, Konada L, Heady L, Rueda R, Jacome ASV, Marlin E, Marchioni C, Segev A, Kritskiy O, Yamakawa S, Reiter AH, Tsai LH, Madabhushi R. Delint-Ramirez I, et al. Among authors: madabhushi r. Mol Cell. 2022 Oct 20;82(20):3794-3809.e8. doi: 10.1016/j.molcel.2022.09.012. Epub 2022 Oct 6. Mol Cell. 2022. PMID: 36206766 Free PMC article.
22 results