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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brönneke HS, Estevez E, Allen TL, Mesaros A, Partridge L, Febbraio MA, Chawla A, Wunderlich FT, Brüning JC. Mauer J, et al. Nat Immunol. 2014 May;15(5):423-30. doi: 10.1038/ni.2865. Epub 2014 Mar 30. Nat Immunol. 2014. PMID: 24681566 Free PMC article.
Versatile functions for IL-6 in metabolism and cancer.
Mauer J, Denson JL, Brüning JC. Mauer J, et al. Trends Immunol. 2015 Feb;36(2):92-101. doi: 10.1016/j.it.2014.12.008. Epub 2015 Jan 21. Trends Immunol. 2015. PMID: 25616716 Review.
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.
Wunderlich CM, Ackermann PJ, Ostermann AL, Adams-Quack P, Vogt MC, Tran ML, Nikolajev A, Waisman A, Garbers C, Theurich S, Mauer J, Hövelmeyer N, Wunderlich FT. Wunderlich CM, et al. Among authors: mauer j. Nat Commun. 2018 Apr 25;9(1):1646. doi: 10.1038/s41467-018-03773-0. Nat Commun. 2018. PMID: 29695802 Free PMC article.
IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis.
Theurich S, Tsaousidou E, Hanssen R, Lempradl AM, Mauer J, Timper K, Schilbach K, Folz-Donahue K, Heilinger C, Sexl V, Pospisilik JA, Wunderlich FT, Brüning JC. Theurich S, et al. Among authors: mauer j. Cell Metab. 2017 Jul 5;26(1):171-184.e6. doi: 10.1016/j.cmet.2017.05.018. Cell Metab. 2017. PMID: 28683285 Free article.
Novel roles for JNK1 in metabolism.
Belgardt BF, Mauer J, Brüning JC. Belgardt BF, et al. Among authors: mauer j. Aging (Albany NY). 2010 Sep;2(9):621-6. doi: 10.18632/aging.100192. Aging (Albany NY). 2010. PMID: 20834068 Free PMC article.
59 results