Ostaszewski BL - Search Results

1

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Hong S, et al. Among authors: ostaszewski bl. Neuron. 2014 Apr 16;82(2):308-19. doi: 10.1016/j.neuron.2014.02.027. Epub 2014 Mar 27. Neuron. 2014. PMID: 24685176 Free PMC article.

2

Detection of distinct isoform patterns of the beta-amyloid precursor protein in human platelets and lymphocytes.

Schlossmacher MG, Ostaszewski BL, Hecker LI, Celi A, Haass C, Chin D, Lieberburg I, Furie BC, Furie B, Selkoe DJ. Schlossmacher MG, et al. Among authors: ostaszewski bl. Neurobiol Aging. 1992 May-Jun;13(3):421-34. doi: 10.1016/0197-4580(92)90117-g. Neurobiol Aging. 1992. PMID: 1625772

3

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.

Podlisny MB, Ostaszewski BL, Squazzo SL, Koo EH, Rydell RE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: ostaszewski bl. J Biol Chem. 1995 Apr 21;270(16):9564-70. doi: 10.1074/jbc.270.16.9564. J Biol Chem. 1995. PMID: 7721886 Free article.

4

Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma.

Biere AL, Ostaszewski B, Stimson ER, Hyman BT, Maggio JE, Selkoe DJ. Biere AL, et al. J Biol Chem. 1996 Dec 20;271(51):32916-22. doi: 10.1074/jbc.271.51.32916. J Biol Chem. 1996. PMID: 8955133 Free article.

5

Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing.

Biere AL, Ostaszewski B, Zhao H, Gillespie S, Younkin SG, Selkoe DJ. Biere AL, et al. Neurobiol Dis. 1995 Jun;2(3):177-87. doi: 10.1006/nbdi.1995.0019. Neurobiol Dis. 1995. PMID: 9174001

6

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

Podlisny MB, Walsh DM, Amarante P, Ostaszewski BL, Stimson ER, Maggio JE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: ostaszewski bl. Biochemistry. 1998 Mar 17;37(11):3602-11. doi: 10.1021/bi972029u. Biochemistry. 1998. PMID: 9521679

7

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ. Citron M, et al. Among authors: ostaszewski bl. Neurobiol Dis. 1998 Aug;5(2):107-16. doi: 10.1006/nbdi.1998.0183. Neurobiol Dis. 1998. PMID: 9746908

8

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ. Xia W, et al. Among authors: ostaszewski bl. Biochemistry. 1998 Nov 24;37(47):16465-71. doi: 10.1021/bi9816195. Biochemistry. 1998. PMID: 9843412

9

Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease.

Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor IO, Selkoe DJ. Wolfe MS, et al. Biochemistry. 1999 Apr 13;38(15):4720-7. doi: 10.1021/bi982562p. Biochemistry. 1999. PMID: 10200159

10

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ. Wolfe MS, et al. Among authors: ostaszewski bl. Nature. 1999 Apr 8;398(6727):513-7. doi: 10.1038/19077. Nature. 1999. PMID: 10206644

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