Zhang J - Search Results

1

Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity.

Li X, Inks ES, Li X, Hou J, Chou CJ, Zhang J, Jiang Y, Zhang Y, Xu W. Li X, et al. Among authors: zhang j, zhang y. J Med Chem. 2014 Apr 24;57(8):3324-41. doi: 10.1021/jm401877m. Epub 2014 Apr 15. J Med Chem. 2014. PMID: 24694055 Free PMC article.

2

Design, synthesis and preliminary evaluation of α-sulfonyl γ-(glycinyl-amino)proline peptidomimetics as matrix metalloproteinase inhibitors.

Zhang J, Li X, Jiang Y, Feng J, Li X, Zhang Y, Xu W. Zhang J, et al. Among authors: zhang y. Bioorg Med Chem. 2014 Jun 1;22(11):3055-64. doi: 10.1016/j.bmc.2013.12.025. Epub 2013 Dec 21. Bioorg Med Chem. 2014. PMID: 24755524

3

Design, synthesis and preliminary biological evaluation of indoline-2,3-dione derivatives as novel HDAC inhibitors.

Jin K, Li S, Li X, Zhang J, Xu W, Li X. Jin K, et al. Among authors: zhang j. Bioorg Med Chem. 2015 Aug 1;23(15):4728-4736. doi: 10.1016/j.bmc.2015.05.048. Epub 2015 Jun 3. Bioorg Med Chem. 2015. PMID: 26100440

4

Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity.

Duan W, Hou J, Chu X, Li X, Zhang J, Li J, Xu W, Zhang Y. Duan W, et al. Among authors: zhang j, zhang y. Bioorg Med Chem. 2015 Aug 1;23(15):4481-4488. doi: 10.1016/j.bmc.2015.06.015. Epub 2015 Jun 20. Bioorg Med Chem. 2015. PMID: 26122774

5

Synthesis of chiral ND-322, ND-364 and ND-364 derivatives as selective inhibitors of human gelatinase.

Yan Y, Chen X, Yang X, Zhang J, Xu W, Zhang Y. Yan Y, et al. Among authors: zhang j, zhang y. Bioorg Med Chem. 2015 Oct 15;23(20):6632-40. doi: 10.1016/j.bmc.2015.09.013. Epub 2015 Sep 7. Bioorg Med Chem. 2015. PMID: 26386821

6

Discovery of Multi-target Anticancer Agents Based on HDAC Inhibitor MS-275 and 5-FU.

Jiang Y, Li X, Li X, Hou J, Ding Y, Zhang J, Xu W, Zhang Y. Jiang Y, et al. Among authors: zhang j, zhang y. Med Chem. 2016;12(1):30-6. doi: 10.2174/1573406411666150714111045. Med Chem. 2016. PMID: 26711240

7

Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.

Jiang Y, Li X, Hou J, Huang Y, Jia Y, Zou M, Zhang J, Wang X, Xu W, Zhang Y. Jiang Y, et al. Among authors: zhang j, zhang y. Eur J Med Chem. 2016 Oct 4;121:649-657. doi: 10.1016/j.ejmech.2016.05.068. Epub 2016 Jun 1. Eur J Med Chem. 2016. PMID: 27322756

8

Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity.

Jiang Y, Hou J, Li X, Huang Y, Wang X, Wu J, Zhang J, Xu W, Zhang Y. Jiang Y, et al. Among authors: zhang j, zhang y. Bioorg Med Chem. 2016 Nov 15;24(22):5787-5795. doi: 10.1016/j.bmc.2016.09.033. Epub 2016 Sep 14. Bioorg Med Chem. 2016. PMID: 27670098

9

Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy.

Jiang Y, Li X, Hou J, Huang Y, Wang X, Jia Y, Wang Q, Xu W, Zhang J, Zhang Y. Jiang Y, et al. Among authors: zhang j, zhang y. Eur J Med Chem. 2018 Jan 1;143:334-347. doi: 10.1016/j.ejmech.2017.11.074. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202398

10

Synthesis and biological evaluation of novel benzofuroxan-based pyrrolidine hydroxamates as matrix metalloproteinase inhibitors with nitric oxide releasing activity.

Zhang H, Wang X, Mao J, Huang Y, Xu W, Duan Y, Zhang J. Zhang H, et al. Among authors: zhang j. Bioorg Med Chem. 2018 Aug 15;26(15):4363-4374. doi: 10.1016/j.bmc.2018.06.023. Epub 2018 Jun 18. Bioorg Med Chem. 2018. PMID: 30093347

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