Liu K - Search Results

1

Epigenetic targets and drug discovery: part 1: histone methylation.

Liu Y, Liu K, Qin S, Xu C, Min J. Liu Y, et al. Among authors: liu k. Pharmacol Ther. 2014 Sep;143(3):275-94. doi: 10.1016/j.pharmthera.2014.03.007. Epub 2014 Apr 2. Pharmacol Ther. 2014. PMID: 24704322 Review.

2

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.

Liu K, Chen C, Guo Y, Lam R, Bian C, Xu C, Zhao DY, Jin J, MacKenzie F, Pawson T, Min J. Liu K, et al. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18398-403. doi: 10.1073/pnas.1013106107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937909 Free PMC article.

3

Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.

Liu K, Guo Y, Liu H, Bian C, Lam R, Liu Y, Mackenzie F, Rojas LA, Reinberg D, Bedford MT, Xu RM, Min J. Liu K, et al. Among authors: liu y, liu h. PLoS One. 2012;7(2):e30375. doi: 10.1371/journal.pone.0030375. Epub 2012 Feb 17. PLoS One. 2012. PMID: 22363433 Free PMC article.

4

Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.

Xu C, Liu K, Tempel W, Demetriades M, Aik W, Schofield CJ, Min J. Xu C, et al. Among authors: liu k. J Biol Chem. 2014 Jun 20;289(25):17299-311. doi: 10.1074/jbc.M114.550350. Epub 2014 Apr 28. J Biol Chem. 2014. PMID: 24778178 Free PMC article.

5

Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.

Qin S, Liu Y, Tempel W, Eram MS, Bian C, Liu K, Senisterra G, Crombet L, Vedadi M, Min J. Qin S, et al. Among authors: liu k, liu y. Nat Commun. 2014 May 23;5:3952. doi: 10.1038/ncomms4952. Nat Commun. 2014. PMID: 24853335 Free article.

6

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain.

Xu C, Wang X, Liu K, Roundtree IA, Tempel W, Li Y, Lu Z, He C, Min J. Xu C, et al. Among authors: liu k. Nat Chem Biol. 2014 Nov;10(11):927-9. doi: 10.1038/nchembio.1654. Epub 2014 Sep 21. Nat Chem Biol. 2014. PMID: 25242552

7

Substrate specificity and biochemical characterization of an adenylation domain from an obligate marine actinomycete.

Shu X, Ma Y, Lu C, Lei M, Liu Y, Liu K, Xiong G, Xia S, Zhao Z, Luo W, Fu Q, Qi C. Shu X, et al. Among authors: liu k, liu y. Biotechnol Lett. 2015 May;37(5):1049-55. doi: 10.1007/s10529-015-1766-8. Epub 2015 Feb 1. Biotechnol Lett. 2015. PMID: 25637590

8

Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation.

Liu K, Liu Y, Lau JL, Min J. Liu K, et al. Among authors: liu y. Pharmacol Ther. 2015 Jul;151:121-40. doi: 10.1016/j.pharmthera.2015.04.001. Epub 2015 Apr 7. Pharmacol Ther. 2015. PMID: 25857453 Review.

9

Structural and functional characterization of the proteins responsible for N6-methyladenosine modification and recognition.

Liu K, Ding Y, Ye W, Liu Y, Yang J, Liu J, Qi C. Liu K, et al. Among authors: liu j, liu y. Curr Protein Pept Sci. 2015 Jun 22. Online ahead of print. Curr Protein Pept Sci. 2015. PMID: 26100282

10

Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.

Xu C, Liu K, Ahmed H, Loppnau P, Schapira M, Min J. Xu C, et al. Among authors: liu k. J Biol Chem. 2015 Oct 9;290(41):24902-13. doi: 10.1074/jbc.M115.680389. Epub 2015 Aug 28. J Biol Chem. 2015. PMID: 26318451 Free PMC article.

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