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STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.
Semper C, Leitner NR, Lassnig C, Parrini M, Mahlakõiv T, Rammerstorfer M, Lorenz K, Rigler D, Müller S, Kolbe T, Vogl C, Rülicke T, Staeheli P, Decker T, Müller M, Strobl B. Semper C, et al. Among authors: staeheli p. Mol Cell Biol. 2014 Jun;34(12):2235-48. doi: 10.1128/MCB.00295-14. Epub 2014 Apr 7. Mol Cell Biol. 2014. PMID: 24710278 Free PMC article.
Human but not mouse hepatocytes respond to interferon-lambda in vivo.
Hermant P, Demarez C, Mahlakõiv T, Staeheli P, Meuleman P, Michiels T. Hermant P, et al. Among authors: staeheli p. PLoS One. 2014 Jan 31;9(1):e87906. doi: 10.1371/journal.pone.0087906. eCollection 2014. PLoS One. 2014. PMID: 24498220 Free PMC article.
Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses.
Schnepf D, Crotta S, Thamamongood T, Stanifer M, Polcik L, Ohnemus A, Vier J, Jakob C, Llorian M, Gad HH, Hartmann R, Strobl B, Kirschnek S, Boulant S, Schwemmle M, Wack A, Staeheli P. Schnepf D, et al. Among authors: staeheli p. Sci Immunol. 2021 May 14;6(59):eabd5318. doi: 10.1126/sciimmunol.abd5318. Sci Immunol. 2021. PMID: 33990378 Free PMC article.
IFN-lambda determines the intestinal epithelial antiviral host defense.
Pott J, Mahlakõiv T, Mordstein M, Duerr CU, Michiels T, Stockinger S, Staeheli P, Hornef MW. Pott J, et al. Among authors: staeheli p. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7944-9. doi: 10.1073/pnas.1100552108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518880 Free PMC article.
Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection.
Hernández PP, Mahlakoiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, Gronke K, Ryffel B, Hoelscher C, Dumoutier L, Renauld JC, Suerbaum S, Staeheli P, Diefenbach A. Hernández PP, et al. Among authors: staeheli p. Nat Immunol. 2015 Jul;16(7):698-707. doi: 10.1038/ni.3180. Epub 2015 May 25. Nat Immunol. 2015. PMID: 26006013 Free PMC article.
254 results