Handy DE - Search Results

1

Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.

Barroso M, Florindo C, Kalwa H, Silva Z, Turanov AA, Carlson BA, de Almeida IT, Blom HJ, Gladyshev VN, Hatfield DL, Michel T, Castro R, Loscalzo J, Handy DE. Barroso M, et al. Among authors: handy de, de almeida it. J Biol Chem. 2014 May 30;289(22):15350-62. doi: 10.1074/jbc.M114.549782. Epub 2014 Apr 9. J Biol Chem. 2014. PMID: 24719327 Free PMC article.

2

Homocysteine and atherothrombosis: diagnosis and treatment.

Handy DE, Loscalzo J. Handy DE, et al. Curr Atheroscler Rep. 2003 Jul;5(4):276-83. doi: 10.1007/s11883-003-0050-x. Curr Atheroscler Rep. 2003. PMID: 12793968 Review.

3

Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.

Jain M, Cui L, Brenner DA, Wang B, Handy DE, Leopold JA, Loscalzo J, Apstein CS, Liao R. Jain M, et al. Among authors: handy de. Circulation. 2004 Feb 24;109(7):898-903. doi: 10.1161/01.CIR.0000112605.43318.CA. Epub 2004 Feb 2. Circulation. 2004. PMID: 14757696

4

Determinants of human plasma glutathione peroxidase (GPx-3) expression.

Bierl C, Voetsch B, Jin RC, Handy DE, Loscalzo J. Bierl C, et al. Among authors: handy de. J Biol Chem. 2004 Jun 25;279(26):26839-45. doi: 10.1074/jbc.M401907200. Epub 2004 Apr 19. J Biol Chem. 2004. PMID: 15096516 Free article.

5

L-arginine increases plasma homocysteine in apoE-/-/iNOS-/- double knockout mice.

Handy DE, Scolaro J, Chen J, Huang P, Loscalzo J. Handy DE, et al. Cell Mol Biol (Noisy-le-grand). 2004 Dec;50(8):903-9. Cell Mol Biol (Noisy-le-grand). 2004. PMID: 15704254

6

Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation.

Handy DE, Zhang Y, Loscalzo J. Handy DE, et al. J Biol Chem. 2005 Apr 22;280(16):15518-25. doi: 10.1074/jbc.M501452200. Epub 2005 Feb 25. J Biol Chem. 2005. PMID: 15734734 Free article.

7

Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress.

Zhang Y, Handy DE, Loscalzo J. Zhang Y, et al. Among authors: handy de. Circ Res. 2005 Apr 29;96(8):831-7. doi: 10.1161/01.RES.0000164401.21929.CF. Epub 2005 Mar 31. Circ Res. 2005. PMID: 15802613

8

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice.

Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD. Kamath AF, et al. Among authors: handy de. Blood. 2006 Jan 15;107(2):591-3. doi: 10.1182/blood-2005-06-2506. Epub 2005 Sep 27. Blood. 2006. PMID: 16189268 Free PMC article.

9

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

Handy DE, Hang G, Scolaro J, Metes N, Razaq N, Yang Y, Loscalzo J. Handy DE, et al. J Biol Chem. 2006 Feb 10;281(6):3382-8. doi: 10.1074/jbc.M511295200. Epub 2005 Dec 14. J Biol Chem. 2006. PMID: 16354666 Free PMC article.

10

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction.

Galasso G, Schiekofer S, Sato K, Shibata R, Handy DE, Ouchi N, Leopold JA, Loscalzo J, Walsh K. Galasso G, et al. Among authors: handy de. Circ Res. 2006 Feb 3;98(2):254-61. doi: 10.1161/01.RES.0000200740.57764.52. Epub 2005 Dec 22. Circ Res. 2006. PMID: 16373599 Free PMC article.

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