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Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.
Wagener J, Malireddi RK, Lenardon MD, Köberle M, Vautier S, MacCallum DM, Biedermann T, Schaller M, Netea MG, Kanneganti TD, Brown GD, Brown AJ, Gow NA. Wagener J, et al. Among authors: schaller m. PLoS Pathog. 2014 Apr 10;10(4):e1004050. doi: 10.1371/journal.ppat.1004050. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722226 Free PMC article. Clinical Trial.
Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells.
Wagener J, Weindl G, de Groot PW, de Boer AD, Kaesler S, Thavaraj S, Bader O, Mailänder-Sanchez D, Borelli C, Weig M, Biedermann T, Naglik JR, Korting HC, Schaller M. Wagener J, et al. Among authors: schaller m. PLoS One. 2012;7(11):e50518. doi: 10.1371/journal.pone.0050518. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226301 Free PMC article.
IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells.
Guenova E, Skabytska Y, Hoetzenecker W, Weindl G, Sauer K, Tham M, Kim KW, Park JH, Seo JH, Ignatova D, Cozzio A, Levesque MP, Volz T, Köberle M, Kaesler S, Thomas P, Mailhammer R, Ghoreschi K, Schäkel K, Amarov B, Eichner M, Schaller M, Clark RA, Röcken M, Biedermann T. Guenova E, et al. Among authors: schaller m. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2163-8. doi: 10.1073/pnas.1416922112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646481 Free PMC article.
A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation.
Wagener J, Schneider JJ, Baxmann S, Kalbacher H, Borelli C, Nuding S, Küchler R, Wehkamp J, Kaeser MD, Mailänder-Sanchez D, Braunsdorf C, Hube B, Schild L, Forssmann WG, Korting HC, Liepke C, Schaller M. Wagener J, et al. Among authors: schaller m. J Invest Dermatol. 2013 Jan;133(1):144-53. doi: 10.1038/jid.2012.254. Epub 2012 Jul 26. J Invest Dermatol. 2013. PMID: 22832495 Free PMC article.
882 results