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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Wu X, et al. Among authors: sharp pa. Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752079 Free PMC article.
Dynamic association of proteins with the pre-mRNA branch region.
MacMillan AM, Query CC, Allerson CR, Chen S, Verdine GL, Sharp PA. MacMillan AM, et al. Among authors: sharp pa. Genes Dev. 1994 Dec 15;8(24):3008-20. doi: 10.1101/gad.8.24.3008. Genes Dev. 1994. PMID: 8001820 Free article.
Cre-lox-regulated conditional RNA interference from transgenes.
Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. Ventura A, et al. Among authors: sharp pa. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10380-5. doi: 10.1073/pnas.0403954101. Epub 2004 Jul 6. Proc Natl Acad Sci U S A. 2004. PMID: 15240889 Free PMC article.
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells.
Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, Hannett N, Sharp PA, Bartel DP, Jaenisch R, Young RA. Marson A, et al. Among authors: sharp pa. Cell. 2008 Aug 8;134(3):521-33. doi: 10.1016/j.cell.2008.07.020. Cell. 2008. PMID: 18692474 Free PMC article.
Histone H3K27ac separates active from poised enhancers and predicts developmental state.
Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Creyghton MP, et al. Among authors: sharp pa. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21931-6. doi: 10.1073/pnas.1016071107. Epub 2010 Nov 24. Proc Natl Acad Sci U S A. 2010. PMID: 21106759 Free PMC article.
510 results