Luijten M - Search Results

1

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.

Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, Groothuis G, Luijten M, Danen E, de Graauw M, Meerman J, van de Water B. Fredriksson L, et al. Among authors: luijten m. Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20. Toxicol Sci. 2014. PMID: 24752500

2

Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.

Robinson JF, van Beelen VA, Verhoef A, Renkens MF, Luijten M, van Herwijnen MH, Westerman A, Pennings JL, Piersma AH. Robinson JF, et al. Among authors: luijten m. Toxicol Sci. 2010 Dec;118(2):675-85. doi: 10.1093/toxsci/kfq292. Epub 2010 Sep 23. Toxicol Sci. 2010. PMID: 20864626

3

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.

van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M. van Kesteren PC, et al. Among authors: luijten m. Toxicol Sci. 2011 Sep;123(1):123-32. doi: 10.1093/toxsci/kfr169. Epub 2011 Jun 29. Toxicol Sci. 2011. PMID: 21715664

4

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.

Schaap MM, Zwart EP, Wackers PF, Huijskens I, van de Water B, Breit TM, van Steeg H, Jonker MJ, Luijten M. Schaap MM, et al. Among authors: luijten m. Arch Toxicol. 2012 Nov;86(11):1717-27. doi: 10.1007/s00204-012-0883-6. Epub 2012 Jun 19. Arch Toxicol. 2012. PMID: 22710402

5

Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.

van Kesteren PC, Zwart PE, Schaap MM, Pronk TE, van Herwijnen MH, Kleinjans JC, Bokkers BG, Godschalk RW, Zeilmaker MJ, van Steeg H, Luijten M. van Kesteren PC, et al. Among authors: luijten m. Arch Toxicol. 2013 Mar;87(3):505-15. doi: 10.1007/s00204-012-0949-5. Epub 2012 Oct 2. Arch Toxicol. 2013. PMID: 23052197

6

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis.

Kienhuis AS, Vitins AP, Pennings JL, Pronk TE, Speksnijder EN, Roodbergen M, van Delft JH, Luijten M, van der Ven LT. Kienhuis AS, et al. Among authors: luijten m. Toxicol Lett. 2013 Aug 29;221(3):225-36. doi: 10.1016/j.toxlet.2013.06.236. Epub 2013 Jul 3. Toxicol Lett. 2013. PMID: 23830897

7

Mechanisms of amiodarone and valproic acid induced liver steatosis in mouse in vivo act as a template for other hepatotoxicity models.

Vitins AP, Kienhuis AS, Speksnijder EN, Roodbergen M, Luijten M, van der Ven LT. Vitins AP, et al. Among authors: luijten m. Arch Toxicol. 2014 Aug;88(8):1573-88. doi: 10.1007/s00204-014-1211-0. Epub 2014 Feb 18. Arch Toxicol. 2014. PMID: 24535564

8

A day and night difference in the response of the hepatic transcriptome to cyclophosphamide treatment.

Van Dycke KC, Nijman RM, Wackers PF, Jonker MJ, Rodenburg W, van Oostrom CT, Salvatori DC, Breit TM, van Steeg H, Luijten M, van der Horst GT. Van Dycke KC, et al. Among authors: luijten m. Arch Toxicol. 2015 Feb;89(2):221-31. doi: 10.1007/s00204-014-1257-z. Epub 2014 May 13. Arch Toxicol. 2015. PMID: 24819615

9

Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models.

Schmeits PC, Schaap MM, Luijten M, van Someren E, Boorsma A, van Loveren H, Peijnenburg AA, Hendriksen PJ. Schmeits PC, et al. Among authors: luijten m. Arch Toxicol. 2015 Dec;89(12):2325-37. doi: 10.1007/s00204-014-1365-9. Epub 2014 Sep 17. Arch Toxicol. 2015. PMID: 25224403

10

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Schaap MM, Wackers PF, Zwart EP, Huijskens I, Jonker MJ, Hendriks G, Breit TM, van Steeg H, van de Water B, Luijten M. Schaap MM, et al. Among authors: luijten m. Arch Toxicol. 2015 Dec;89(12):2413-27. doi: 10.1007/s00204-014-1368-6. Epub 2014 Oct 2. Arch Toxicol. 2015. PMID: 25270620

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