Meerman J - Search Results

1

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.

Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, Groothuis G, Luijten M, Danen E, de Graauw M, Meerman J, van de Water B. Fredriksson L, et al. Among authors: meerman j. Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20. Toxicol Sci. 2014. PMID: 24752500

2

TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells.

Benedetti G, Fredriksson L, Herpers B, Meerman J, van de Water B, de Graauw M. Benedetti G, et al. Among authors: meerman j. Biochem Pharmacol. 2013 Jan 15;85(2):274-86. doi: 10.1016/j.bcp.2012.10.012. Epub 2012 Oct 24. Biochem Pharmacol. 2013. PMID: 23103562

3

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.

Hiemstra S, Ramaiahgari SC, Wink S, Callegaro G, Coonen M, Meerman J, Jennen D, van den Nieuwendijk K, Dankers A, Snoeys J, de Bont H, Price L, van de Water B. Hiemstra S, et al. Among authors: meerman j. Arch Toxicol. 2019 Oct;93(10):2895-2911. doi: 10.1007/s00204-019-02552-0. Epub 2019 Aug 27. Arch Toxicol. 2019. PMID: 31552476

4

The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switch.

Benedetti G, Fokkelman M, Yan K, Fredriksson L, Herpers B, Meerman J, van de Water B, de Graauw M. Benedetti G, et al. Among authors: meerman j. Mol Pharmacol. 2013 Jul;84(1):128-38. doi: 10.1124/mol.112.084053. Epub 2013 Apr 26. Mol Pharmacol. 2013. PMID: 23625948

5

Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.

Di Z, Herpers B, Fredriksson L, Yan K, van de Water B, Verbeek FJ, Meerman JH. Di Z, et al. Among authors: meerman jh. PLoS One. 2012;7(12):e52337. doi: 10.1371/journal.pone.0052337. Epub 2012 Dec 27. PLoS One. 2012. PMID: 23300644 Free PMC article.

6

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.

Zhang Y, Moerkens M, Ramaiahgari S, de Bont H, Price L, Meerman J, van de Water B. Zhang Y, et al. Among authors: meerman j. Breast Cancer Res. 2011 May 19;13(3):R52. doi: 10.1186/bcr2883. Breast Cancer Res. 2011. PMID: 21595894 Free PMC article.

7

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation.

Moerkens M, Zhang Y, Wester L, van de Water B, Meerman JH. Moerkens M, et al. BMC Cancer. 2014 Apr 23;14:283. doi: 10.1186/1471-2407-14-283. BMC Cancer. 2014. PMID: 24758408 Free PMC article.

8

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.

Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH. Carreras Puigvert J, et al. Among authors: meerman jh. Sci Signal. 2013 Jan 22;6(259):ra5. doi: 10.1126/scisignal.2003208. Sci Signal. 2013. PMID: 23354688

9

Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.

Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, Koster J, Danen EH, van de Water B, Versteeg R, Fitzsimons CP, Vreugdenhil E. Verissimo CS, et al. Among authors: meerman j. Endocr Relat Cancer. 2010 Apr 21;17(2):399-414. doi: 10.1677/ERC-09-0301. Print 2010 Jun. Endocr Relat Cancer. 2010. PMID: 20228126

10

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioğlu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH. Truong HH, et al. Among authors: meerman jh. Sci Signal. 2014 Feb 11;7(312):ra15. doi: 10.1126/scisignal.2004751. Sci Signal. 2014. PMID: 24518294

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