de Graauw M - Search Results

1

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.

Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, Groothuis G, Luijten M, Danen E, de Graauw M, Meerman J, van de Water B. Fredriksson L, et al. Among authors: de graauw m. Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20. Toxicol Sci. 2014. PMID: 24752500

2

Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis.

Fredriksson L, Herpers B, Benedetti G, Matadin Q, Puigvert JC, de Bont H, Dragovic S, Vermeulen NP, Commandeur JN, Danen E, de Graauw M, van de Water B. Fredriksson L, et al. Among authors: de graauw m, de bont h. Hepatology. 2011 Jun;53(6):2027-41. doi: 10.1002/hep.24314. Hepatology. 2011. PMID: 21433042

3

TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells.

Benedetti G, Fredriksson L, Herpers B, Meerman J, van de Water B, de Graauw M. Benedetti G, et al. Among authors: de graauw m. Biochem Pharmacol. 2013 Jan 15;85(2):274-86. doi: 10.1016/j.bcp.2012.10.012. Epub 2012 Oct 24. Biochem Pharmacol. 2013. PMID: 23103562

4

A screen for apoptotic synergism between clinical relevant nephrotoxicant and the cytokine TNF-α.

Benedetti G, Ramaiahgaris S, Herpers B, van de Water B, Price LS, de Graauw M. Benedetti G, et al. Among authors: de graauw m. Toxicol In Vitro. 2013 Dec;27(8):2264-72. doi: 10.1016/j.tiv.2013.09.004. Epub 2013 Sep 13. Toxicol In Vitro. 2013. PMID: 24041534

5

Cellular stress responses and molecular mechanisms of nephrotoxicity.

van de Water B, de Graauw M, Le Dévédec S, Alderliesten M. van de Water B, et al. Among authors: de graauw m. Toxicol Lett. 2006 Mar 15;162(1):83-93. doi: 10.1016/j.toxlet.2005.10.014. Epub 2005 Dec 15. Toxicol Lett. 2006. PMID: 16359832 Review.

6

The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switch.

Benedetti G, Fokkelman M, Yan K, Fredriksson L, Herpers B, Meerman J, van de Water B, de Graauw M. Benedetti G, et al. Among authors: de graauw m. Mol Pharmacol. 2013 Jul;84(1):128-38. doi: 10.1124/mol.112.084053. Epub 2013 Apr 26. Mol Pharmacol. 2013. PMID: 23625948

7

Phospho-proteomic analysis of cellular signaling.

de Graauw M, Hensbergen P, van de Water B. de Graauw M, et al. Electrophoresis. 2006 Jul;27(13):2676-86. doi: 10.1002/elps.200600018. Electrophoresis. 2006. PMID: 16739229 Review.

8

Protein kinase C mediates cisplatin-induced loss of adherens junctions followed by apoptosis of renal proximal tubular epithelial cells.

Imamdi R, de Graauw M, van de Water B. Imamdi R, et al. Among authors: de graauw m. J Pharmacol Exp Ther. 2004 Dec;311(3):892-903. doi: 10.1124/jpet.104.072678. Epub 2004 Sep 20. J Pharmacol Exp Ther. 2004. PMID: 15381733

9

Proteomic analysis of alternative protein tyrosine phosphorylation in 1,2-dichlorovinyl-cysteine-induced cytotoxicity in primary cultured rat renal proximal tubular cells.

de Graauw M, Le Dévédec S, Tijdens I, Smeets MB, Deelder AM, van de Water B. de Graauw M, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):89-100. doi: 10.1124/jpet.106.117689. Epub 2007 Apr 18. J Pharmacol Exp Ther. 2007. PMID: 17442843

10

cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac.

Qin Y, Stokman G, Yan K, Ramaiahgari S, Verbeek F, de Graauw M, van de Water B, Price LS. Qin Y, et al. Among authors: de graauw m. Br J Pharmacol. 2012 Feb;165(4b):1137-50. doi: 10.1111/j.1476-5381.2011.01594.x. Br J Pharmacol. 2012. PMID: 21745194 Free PMC article.

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