De Francesco R - Search Results

1

Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors.

McGivern DR, Masaki T, Williford S, Ingravallo P, Feng Z, Lahser F, Asante-Appiah E, Neddermann P, De Francesco R, Howe AY, Lemon SM. McGivern DR, et al. Among authors: de francesco r. Gastroenterology. 2014 Aug;147(2):453-62.e7. doi: 10.1053/j.gastro.2014.04.021. Epub 2014 Apr 22. Gastroenterology. 2014. PMID: 24768676 Free PMC article.

2

The nonstructural proteins of the hepatitis C virus: structure and functions.

Neddermann P, Tomei L, Steinkühler C, Gallinari P, Tramontano A, De Francesco R. Neddermann P, et al. Among authors: de francesco r. Biol Chem. 1997 Jun;378(6):469-76. Biol Chem. 1997. PMID: 9224925 Review.

3

Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products.

Ingallinella P, Altamura S, Bianchi E, Taliani M, Ingenito R, Cortese R, De Francesco R, Steinkühler C, Pessi A. Ingallinella P, et al. Among authors: de francesco r. Biochemistry. 1998 Jun 23;37(25):8906-14. doi: 10.1021/bi980314n. Biochemistry. 1998. PMID: 9636032

4

Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein.

Neddermann P, Clementi A, De Francesco R. Neddermann P, et al. Among authors: de francesco r. J Virol. 1999 Dec;73(12):9984-91. doi: 10.1128/JVI.73.12.9984-9991.1999. J Virol. 1999. PMID: 10559312 Free PMC article.

5

Molecular virology of the hepatitis C virus.

De Francesco R. De Francesco R. J Hepatol. 1999;31 Suppl 1:47-53. doi: 10.1016/s0168-8278(99)80374-2. J Hepatol. 1999. PMID: 10622560 Review.

6

Mechanisms of hepatitis C virus NS3 proteinase inhibitors.

De Francesco R, Pessi A, Steinkühler C. De Francesco R, et al. J Viral Hepat. 1999 Jul;6 Suppl 1:23-30. doi: 10.1046/j.1365-2893.1999.00002.x. J Viral Hepat. 1999. PMID: 10760031 Review.

7

Biochemical and immunologic properties of the nonstructural proteins of the hepatitis C virus: implications for development of antiviral agents and vaccines.

De Francesco R, Neddermann P, Tomei L, Steinkühler C, Gallinari P, Folgori A. De Francesco R, et al. Semin Liver Dis. 2000;20(1):69-83. doi: 10.1055/s-2000-9504. Semin Liver Dis. 2000. PMID: 10895433 Review.

8

Measurement of homonuclear three-bond J(H(N)Halpha) coupling constants in unlabeled peptides complexed with labeled proteins: application to a decapeptide inhibitor bound to the proteinase domain of the NS3 protein of hepatitis C virus (HCV).

Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Sambucini S, Neddermann P, De Francesco R, Pessi A, Bazzo R. Cicero DO, et al. Among authors: de francesco r. J Biomol NMR. 2001 May;20(1):23-9. doi: 10.1023/a:1011281527761. J Biomol NMR. 2001. PMID: 11430752

9

A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR.

Neddermann P, Gargioli C, Muraglia E, Sambucini S, Bonelli F, De Francesco R, Cortese R. Neddermann P, et al. Among authors: de francesco r. EMBO Rep. 2003 Feb;4(2):159-65. doi: 10.1038/sj.embor.embor734. EMBO Rep. 2003. PMID: 12612605 Free PMC article.

10

Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.

De Francesco R, Tomei L, Altamura S, Summa V, Migliaccio G. De Francesco R, et al. Antiviral Res. 2003 Mar;58(1):1-16. doi: 10.1016/s0166-3542(03)00028-7. Antiviral Res. 2003. PMID: 12719002 Review.

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