Routier S - Search Results

1

Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors.

Dehbi O, Tikad A, Bourg S, Bonnet P, Lozach O, Meijer L, Aadil M, Akssira M, Guillaumet G, Routier S. Dehbi O, et al. Among authors: routier s. Eur J Med Chem. 2014 Jun 10;80:352-63. doi: 10.1016/j.ejmech.2014.04.055. Epub 2014 Apr 22. Eur J Med Chem. 2014. PMID: 24793883

2

Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents.

Routier S, Peixoto P, Mérour JY, Coudert G, Dias N, Bailly C, Pierré A, Léonce S, Caignard DH. Routier S, et al. J Med Chem. 2005 Mar 10;48(5):1401-13. doi: 10.1021/jm049213f. J Med Chem. 2005. PMID: 15743184

3

Synthesis of 2,5- and 3,5-diphenylpyridine derivatives for DNA recognition and cytotoxicity.

Jacquemard U, Routier S, Dias N, Lansiaux A, Goossens JF, Bailly C, Mérour JY. Jacquemard U, et al. Among authors: routier s. Eur J Med Chem. 2005 Nov;40(11):1087-95. doi: 10.1016/j.ejmech.2005.04.011. Epub 2005 Jun 13. Eur J Med Chem. 2005. PMID: 15951061

4

Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.

Routier S, Mérour JY, Dias N, Lansiaux A, Bailly C, Lozach O, Meijer L. Routier S, et al. J Med Chem. 2006 Jan 26;49(2):789-99. doi: 10.1021/jm050945x. J Med Chem. 2006. PMID: 16420063

5

2,6-Quinolinyl derivatives as potent VLA-4 antagonists.

Lassoie MA, Broeders F, Collart P, Defrère L, de Laveleye-Defais F, Demaude T, Gassama A, Guillaumet G, Hayez JC, Kiss L, Knerr L, Nicolas JM, Norsikian S, Quéré L, Routier S, Verbois V, Provins L. Lassoie MA, et al. Among authors: routier s. Bioorg Med Chem Lett. 2007 Jan 1;17(1):142-6. doi: 10.1016/j.bmcl.2006.09.069. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17035017

6

New efficient route to dissymmetric 2,4-di(het)aryl-pyrido[3,2-d]pyrimidines via regioselective cross-coupling reactions.

Tikad A, Routier S, Akssira M, Leger JM, Jarry C, Guillaumet G. Tikad A, et al. Among authors: routier s. Org Lett. 2007 Nov 8;9(23):4673-6. doi: 10.1021/ol7014434. Epub 2007 Oct 20. Org Lett. 2007. PMID: 17949094

7

Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.

Lefoix M, Coudert G, Routier S, Pfeiffer B, Caignard DH, Hickman J, Pierré A, Golsteyn RM, Léonce S, Bossard C, Mérour JY. Lefoix M, et al. Among authors: routier s. Bioorg Med Chem. 2008 May 1;16(9):5303-21. doi: 10.1016/j.bmc.2008.02.086. Epub 2008 Mar 4. Bioorg Med Chem. 2008. PMID: 18342518

8

Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents.

Jacquemard U, Dias N, Lansiaux A, Bailly C, Logé C, Robert JM, Lozach O, Meijer L, Mérour JY, Routier S. Jacquemard U, et al. Among authors: routier s. Bioorg Med Chem. 2008 May 1;16(9):4932-53. doi: 10.1016/j.bmc.2008.03.034. Epub 2008 Mar 17. Bioorg Med Chem. 2008. PMID: 18439832

9

Efficient one-pot synthesis of 2,4-di(het)aryl and 2,4-diamino pyrido[3,2-d]pyrimidines involving regioselective S(N)Ar and palladium-catalyzed reactions.

Tikad A, Routier S, Akssira M, Guillaumet G. Tikad A, et al. Among authors: routier s. Org Biomol Chem. 2009 Dec 21;7(24):5113-8. doi: 10.1039/b913657f. Epub 2009 Oct 15. Org Biomol Chem. 2009. PMID: 20024106

10

Synthesis and biological evaluation of novel benzodioxinocarbazoles (BDCZs) as potential anticancer agents.

Ayerbe N, Routier S, Gillaizeau I, Maiereanu C, Caignard DH, Pierré A, Léonce S, Coudert G. Ayerbe N, et al. Among authors: routier s. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4670-4. doi: 10.1016/j.bmcl.2010.05.088. Epub 2010 May 26. Bioorg Med Chem Lett. 2010. PMID: 20566289

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