Radle MI - Search Results

1

Characterization of a cross-linked protein-nucleic acid substrate radical in the reaction catalyzed by RlmN.

Silakov A, Grove TL, Radle MI, Bauerle MR, Green MT, Rosenzweig AC, Boal AK, Booker SJ. Silakov A, et al. Among authors: radle mi. J Am Chem Soc. 2014 Jun 11;136(23):8221-8. doi: 10.1021/ja410560p. Epub 2014 Jun 2. J Am Chem Soc. 2014. PMID: 24806349 Free PMC article.

2

A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.

Grove TL, Benner JS, Radle MI, Ahlum JH, Landgraf BJ, Krebs C, Booker SJ. Grove TL, et al. Among authors: radle mi. Science. 2011 Apr 29;332(6029):604-7. doi: 10.1126/science.1200877. Epub 2011 Mar 17. Science. 2011. PMID: 21415317

3

Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.

Grove TL, Radle MI, Krebs C, Booker SJ. Grove TL, et al. Among authors: radle mi. J Am Chem Soc. 2011 Dec 14;133(49):19586-9. doi: 10.1021/ja207327v. Epub 2011 Nov 18. J Am Chem Soc. 2011. PMID: 21916495 Free PMC article.

4

Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.

Grove TL, Ahlum JH, Qin RM, Lanz ND, Radle MI, Krebs C, Booker SJ. Grove TL, et al. Among authors: radle mi. Biochemistry. 2013 Apr 30;52(17):2874-87. doi: 10.1021/bi400136u. Epub 2013 Apr 16. Biochemistry. 2013. PMID: 23477283 Free PMC article.

5

Methanogenesis marker protein 10 (Mmp10) from Methanosarcina acetivorans is a radical S-adenosylmethionine methylase that unexpectedly requires cobalamin.

Radle MI, Miller DV, Laremore TN, Booker SJ. Radle MI, et al. J Biol Chem. 2019 Aug 2;294(31):11712-11725. doi: 10.1074/jbc.RA119.007609. Epub 2019 May 20. J Biol Chem. 2019. PMID: 31113866 Free PMC article.

6

First Step in Catalysis of the Radical S-Adenosylmethionine Methylthiotransferase MiaB Yields an Intermediate with a [3Fe-4S]⁰-Like Auxiliary Cluster.

Zhang B, Arcinas AJ, Radle MI, Silakov A, Booker SJ, Krebs C. Zhang B, et al. Among authors: radle mi. J Am Chem Soc. 2020 Jan 29;142(4):1911-1924. doi: 10.1021/jacs.9b11093. Epub 2020 Jan 16. J Am Chem Soc. 2020. PMID: 31899624 Free PMC article.

7

Evidence that histidine forms a coordination bond to the A(0A) and A(0B) chlorophylls and a second H-bond to the A(1A) and A(1B) phylloquinones in M688H(PsaA) and M668H(PsaB) variants of Synechocystis sp. PCC 6803.

Sun J, Hao S, Radle M, Xu W, Shelaev I, Nadtochenko V, Shuvalov V, Semenov A, Gordon H, van der Est A, Golbeck JH. Sun J, et al. Biochim Biophys Acta. 2014 Aug;1837(8):1362-75. doi: 10.1016/j.bbabio.2014.04.004. Epub 2014 Apr 16. Biochim Biophys Acta. 2014. PMID: 24747069 Free article.

8

Engineered biosynthesis of bacteriochlorophyll g_F in Rhodobacter sphaeroides.

Ortega-Ramos M, Canniffe DP, Radle MI, Neil Hunter C, Bryant DA, Golbeck JH. Ortega-Ramos M, et al. Among authors: radle mi. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):501-509. doi: 10.1016/j.bbabio.2018.02.006. Epub 2018 Feb 26. Biochim Biophys Acta Bioenerg. 2018. PMID: 29496394 Free article.

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