van Echten-Deckert G - Search Results

1

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.

Karaca I, Tamboli IY, Glebov K, Richter J, Fell LH, Grimm MO, Haupenthal VJ, Hartmann T, Gräler MH, van Echten-Deckert G, Walter J. Karaca I, et al. J Biol Chem. 2014 Jun 13;289(24):16761-72. doi: 10.1074/jbc.M113.535500. Epub 2014 May 7. J Biol Chem. 2014. PMID: 24808180 Free PMC article.

2

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide.

Michel C, van Echten-Deckert G, Rother J, Sandhoff K, Wang E, Merrill AH Jr. Michel C, et al. J Biol Chem. 1997 Sep 5;272(36):22432-7. doi: 10.1074/jbc.272.36.22432. J Biol Chem. 1997. PMID: 9312549 Free article.

3

Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts.

van Echten-Deckert G, Schick A, Heinemann T, Schnieders B. van Echten-Deckert G, et al. J Biol Chem. 1998 Sep 4;273(36):23585-9. doi: 10.1074/jbc.273.36.23585. J Biol Chem. 1998. PMID: 9722598 Free article.

4

Cis-4-methylsphingosine phosphate induces apoptosis in neuroblastoma cells by opposite effects on p38 and ERK mitogen-activated protein kinases.

Nätzker S, Heinemann T, Figueroa-Perez S, Schnieders B, Schmidt RR, Sandhoff K, van Echten-Deckert G. Nätzker S, et al. Biol Chem. 2002 Dec;383(12):1885-94. doi: 10.1515/BC.2002.212. Biol Chem. 2002. PMID: 12553725

5

Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons.

Hagen N, Van Veldhoven PP, Proia RL, Park H, Merrill AH Jr, van Echten-Deckert G. Hagen N, et al. J Biol Chem. 2009 Apr 24;284(17):11346-53. doi: 10.1074/jbc.M807336200. Epub 2009 Feb 27. J Biol Chem. 2009. PMID: 19251691 Free PMC article.

6

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.

Hagen N, Hans M, Hartmann D, Swandulla D, van Echten-Deckert G. Hagen N, et al. Cell Death Differ. 2011 Aug;18(8):1356-65. doi: 10.1038/cdd.2011.7. Epub 2011 Feb 18. Cell Death Differ. 2011. PMID: 21331079 Free PMC article.

7

Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons.

Hagen-Euteneuer N, Lütjohann D, Park H, Merrill AH Jr, van Echten-Deckert G. Hagen-Euteneuer N, et al. J Biol Chem. 2012 Mar 16;287(12):9128-36. doi: 10.1074/jbc.M111.302380. Epub 2012 Jan 30. J Biol Chem. 2012. PMID: 22291021 Free PMC article.

8

Sphingolipids: critical players in Alzheimer's disease.

van Echten-Deckert G, Walter J. van Echten-Deckert G, et al. Prog Lipid Res. 2012 Oct;51(4):378-93. doi: 10.1016/j.plipres.2012.07.001. Epub 2012 Jul 23. Prog Lipid Res. 2012. PMID: 22835784 Review.

9

Cross-talk of membrane lipids and Alzheimer-related proteins.

Walter J, van Echten-Deckert G. Walter J, et al. Mol Neurodegener. 2013 Oct 22;8:34. doi: 10.1186/1750-1326-8-34. Mol Neurodegener. 2013. PMID: 24148205 Free PMC article. Review.

10

Sphingosine-1-phosphate: boon and bane for the brain.

van Echten-Deckert G, Hagen-Euteneuer N, Karaca I, Walter J. van Echten-Deckert G, et al. Cell Physiol Biochem. 2014;34(1):148-57. doi: 10.1159/000362991. Epub 2014 Jun 16. Cell Physiol Biochem. 2014. PMID: 24977488 Free article. Review.

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