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Isoniazid mediates the CYP2B6*6 genotype-dependent interaction between efavirenz and antituberculosis drug therapy through mechanism-based inactivation of CYP2A6.
Court MH, Almutairi FE, Greenblatt DJ, Hazarika S, Sheng H, Klein K, Zanger UM, Bourgea J, Patten CJ, Kwara A. Court MH, et al. Among authors: patten cj. Antimicrob Agents Chemother. 2014 Jul;58(7):4145-52. doi: 10.1128/AAC.02532-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820076 Free PMC article.
A high-throughput screen to identify inhibitors of aromatase (CYP19).
Stresser DM, Turner SD, McNamara J, Stocker P, Miller VP, Crespi CL, Patten CJ. Stresser DM, et al. Among authors: patten cj. Anal Biochem. 2000 Sep 10;284(2):427-30. doi: 10.1006/abio.2000.4729. Anal Biochem. 2000. PMID: 10964434 No abstract available.
54 results