O'Donoghue AC - Search Results

1

Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.

Zhai X, Go MK, O'Donoghue AC, Amyes TL, Pegan SD, Wang Y, Loria JP, Mesecar AD, Richard JP. Zhai X, et al. Biochemistry. 2014 Jun 3;53(21):3486-501. doi: 10.1021/bi500458t. Epub 2014 May 22. Biochemistry. 2014. PMID: 24825099 Free PMC article.

2

Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase.

Amyes TL, O'Donoghue AC, Richard JP. Amyes TL, et al. J Am Chem Soc. 2001 Nov 14;123(45):11325-6. doi: 10.1021/ja016754a. J Am Chem Soc. 2001. PMID: 11697989 No abstract available.

3

Formation and stability of enolates of acetamide and acetate anion: an Eigen plot for proton transfer at alpha-carbonyl carbon.

Richard JP, Williams G, O'Donoghue AC, Amyes TL. Richard JP, et al. J Am Chem Soc. 2002 Mar 27;124(12):2957-68. doi: 10.1021/ja0125321. J Am Chem Soc. 2002. PMID: 11902887

4

Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of (R)-glyceraldehyde 3-phosphate in D2O.

O'Donoghue AC, Amyes TL, Richard JP. O'Donoghue AC, et al. Biochemistry. 2005 Feb 22;44(7):2610-21. doi: 10.1021/bi047954c. Biochemistry. 2005. PMID: 15709774

5

Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of dihydroxyacetone phosphate in D2O.

O'Donoghue AC, Amyes TL, Richard JP. O'Donoghue AC, et al. Biochemistry. 2005 Feb 22;44(7):2622-31. doi: 10.1021/bi047953k. Biochemistry. 2005. PMID: 15709775

6

Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside.

O'Donoghue A, Pyun SY, Yang MY, Morrow JR, Richard JP. O'Donoghue A, et al. J Am Chem Soc. 2006 Feb 8;128(5):1615-21. doi: 10.1021/ja056167f. J Am Chem Soc. 2006. PMID: 16448134

7

Slow proton transfer from the hydrogen-labelled carboxylic acid side chain (Glu-165) of triosephosphate isomerase to imidazole buffer in D2O.

O'Donoghue AC, Amyes TL, Richard JP. O'Donoghue AC, et al. Org Biomol Chem. 2008 Jan 21;6(2):391-6. doi: 10.1039/b714304d. Epub 2007 Dec 7. Org Biomol Chem. 2008. PMID: 18175010

8

Keto-enol/enolate equilibria in the N-acetylamino-p-methylacetophenone system. Effect of a beta-nitrogen substituent.

Chiang Y, Griesbeck AG, Heckroth H, Hellrung B, Kresge AJ, Meng Q, O'Donoghue AC, Richard JP, Wirz J. Chiang Y, et al. J Am Chem Soc. 2001 Sep 19;123(37):8979-84. doi: 10.1021/ja0107529. J Am Chem Soc. 2001. PMID: 11552805

9

peri-Dimethylamino substituent effects on proton transfer at carbon in α-naphthylacetate esters: a model for mandelate racemase.

Delley RJ, Bandyopadhyay S, Fox MA, Schliehe C, Hodgson DR, Hollfelder F, Kirby AJ, O'Donoghue AC. Delley RJ, et al. Org Biomol Chem. 2012 Jan 21;10(3):590-6. doi: 10.1039/c1ob06525d. Epub 2011 Nov 23. Org Biomol Chem. 2012. PMID: 22108698

10

Hydrolysis studies of phosphodichloridate and thiophosphodichloridate ions.

Delley RJ, O'Donoghue AC, Hodgson DR. Delley RJ, et al. J Org Chem. 2012 Jul 6;77(13):5829-31. doi: 10.1021/jo300808m. Epub 2012 Jun 18. J Org Chem. 2012. PMID: 22681395 Free article.

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