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Identification of metabolites of N-(5-benzoyl-2-(4-(2-methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide including CYP3A4-mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass.
Song M, Lee D, Kim S, Bae JS, Lee J, Gong YD, Lee T, Lee S. Song M, et al. Among authors: lee d, lee t, lee j, lee s. Drug Metab Dispos. 2014 Aug;42(8):1252-60. doi: 10.1124/dmd.114.057570. Epub 2014 May 14. Drug Metab Dispos. 2014. PMID: 24829290
CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.
Wu Z, Lee D, Joo J, Shin JH, Kang W, Oh S, Lee DY, Lee SJ, Yea SS, Lee HS, Lee T, Liu KH. Wu Z, et al. Among authors: lee dy, lee d, lee t, lee sj, lee hs. Antimicrob Agents Chemother. 2013 Nov;57(11):5448-56. doi: 10.1128/AAC.00843-13. Epub 2013 Aug 19. Antimicrob Agents Chemother. 2013. PMID: 23959307 Free PMC article.
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