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Human Hsp60 with its mitochondrial import signal occurs in solution as heptamers and tetradecamers remarkably stable over a wide range of concentrations.
Vilasi S, Carrotta R, Mangione MR, Campanella C, Librizzi F, Randazzo L, Martorana V, Marino Gammazza A, Ortore MG, Vilasi A, Pocsfalvi G, Burgio G, Corona D, Palumbo Piccionello A, Zummo G, Bulone D, Conway de Macario E, Macario AJ, San Biagio PL, Cappello F. Vilasi S, et al. Among authors: campanella c. PLoS One. 2014 May 15;9(5):e97657. doi: 10.1371/journal.pone.0097657. eCollection 2014. PLoS One. 2014. PMID: 24830947 Free PMC article.
Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells.
Campanella C, Bucchieri F, Ardizzone NM, Marino Gammazza A, Montalbano A, Ribbene A, Di Felice V, Bellafiore M, David S, Rappa F, Marasà M, Peri G, Farina F, Czarnecka AM, Conway de Macario E, Macario AJ, Zummo G, Cappello F. Campanella C, et al. Eur J Histochem. 2008 Oct-Dec;52(4):221-8. doi: 10.4081/1220. Eur J Histochem. 2008. PMID: 19109096
Hsp60 is actively secreted by human tumor cells.
Merendino AM, Bucchieri F, Campanella C, Marcianò V, Ribbene A, David S, Zummo G, Burgio G, Corona DF, Conway de Macario E, Macario AJ, Cappello F. Merendino AM, et al. Among authors: campanella c. PLoS One. 2010 Feb 16;5(2):e9247. doi: 10.1371/journal.pone.0009247. PLoS One. 2010. PMID: 20169074 Free PMC article.
Convergent sets of data from in vivo and in vitro methods point to an active role of Hsp60 in chronic obstructive pulmonary disease pathogenesis.
Cappello F, Caramori G, Campanella C, Vicari C, Gnemmi I, Zanini A, Spanevello A, Capelli A, La Rocca G, Anzalone R, Bucchieri F, D'Anna SE, Ricciardolo FL, Brun P, Balbi B, Carone M, Zummo G, Conway de Macario E, Macario AJ, Di Stefano A. Cappello F, et al. Among authors: campanella c. PLoS One. 2011;6(11):e28200. doi: 10.1371/journal.pone.0028200. Epub 2011 Nov 28. PLoS One. 2011. PMID: 22140545 Free PMC article.
209 results