Shinohara H - Search Results

1

Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation.

Shinohara H, Behar M, Inoue K, Hiroshima M, Yasuda T, Nagashima T, Kimura S, Sanjo H, Maeda S, Yumoto N, Ki S, Akira S, Sako Y, Hoffmann A, Kurosaki T, Okada-Hatakeyama M. Shinohara H, et al. Science. 2014 May 16;344(6185):760-4. doi: 10.1126/science.1250020. Science. 2014. PMID: 24833394

2

Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding.

Shinohara H, Yasuda T, Yamanashi Y. Shinohara H, et al. Genes Cells. 2004 Jun;9(6):601-7. doi: 10.1111/j.1356-9597.2004.00748.x. Genes Cells. 2004. PMID: 15189452 Free article.

3

Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling.

Shinohara H, Inoue A, Toyama-Sorimachi N, Nagai Y, Yasuda T, Suzuki H, Horai R, Iwakura Y, Yamamoto T, Karasuyama H, Miyake K, Yamanashi Y. Shinohara H, et al. J Exp Med. 2005 Feb 7;201(3):333-9. doi: 10.1084/jem.20041817. J Exp Med. 2005. PMID: 15699069 Free PMC article.

4

PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1.

Shinohara H, Yasuda T, Aiba Y, Sanjo H, Hamadate M, Watarai H, Sakurai H, Kurosaki T. Shinohara H, et al. J Exp Med. 2005 Nov 21;202(10):1423-31. doi: 10.1084/jem.20051591. J Exp Med. 2005. PMID: 16301747 Free PMC article.

5

Genetic analysis of B cell signaling.

Shinohara H, Kurosaki T. Shinohara H, et al. Subcell Biochem. 2006;40:145-87. doi: 10.1007/978-1-4020-4896-8_10. Subcell Biochem. 2006. PMID: 17623905 Review.

6

IkappaB kinase beta-induced phosphorylation of CARMA1 contributes to CARMA1 Bcl10 MALT1 complex formation in B cells.

Shinohara H, Maeda S, Watarai H, Kurosaki T. Shinohara H, et al. J Exp Med. 2007 Dec 24;204(13):3285-93. doi: 10.1084/jem.20070379. Epub 2007 Dec 17. J Exp Med. 2007. PMID: 18086859 Free PMC article.

Protein kinase C (PKC) beta has been reported (Shinohara, H., T. Yasuda, Y. Aiba, H. Sanjo, M. Hamadate, H. Watarai, H. Sakurai, and T. ...

Protein kinase C (PKC) beta has been reported (Shinohara, H., T. Yasuda, Y. Aiba, H. Sanjo, M. Hamadate, H. Wata …

7

Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen.

Weber M, Treanor B, Depoil D, Shinohara H, Harwood NE, Hikida M, Kurosaki T, Batista FD. Weber M, et al. Among authors: shinohara h. J Exp Med. 2008 Apr 14;205(4):853-68. doi: 10.1084/jem.20072619. Epub 2008 Mar 24. J Exp Med. 2008. PMID: 18362175 Free PMC article.

8

Regulation of NF-kappaB-dependent T cell activation and development by MEKK3.

Shinohara H, Yamasaki S, Maeda S, Saito T, Kurosaki T. Shinohara H, et al. Int Immunol. 2009 Apr;21(4):393-401. doi: 10.1093/intimm/dxp007. Epub 2009 Feb 17. Int Immunol. 2009. PMID: 19223432

9

B cell signaling and fate decision.

Kurosaki T, Shinohara H, Baba Y. Kurosaki T, et al. Among authors: shinohara h. Annu Rev Immunol. 2010;28:21-55. doi: 10.1146/annurev.immunol.021908.132541. Annu Rev Immunol. 2010. PMID: 19827951 Review.

10

Comprehending the complex connection between PKCbeta, TAK1, and IKK in BCR signaling.

Shinohara H, Kurosaki T. Shinohara H, et al. Immunol Rev. 2009 Nov;232(1):300-18. doi: 10.1111/j.1600-065X.2009.00836.x. Immunol Rev. 2009. PMID: 19909372 Review.

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