Deng G - Search Results

1

Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.

Xiao Y, Nagai Y, Deng G, Ohtani T, Zhu Z, Zhou Z, Zhang H, Ji MQ, Lough JW, Samanta A, Hancock WW, Greene MI. Xiao Y, et al. Among authors: deng g. Cell Rep. 2014 Jun 12;7(5):1471-1480. doi: 10.1016/j.celrep.2014.04.021. Epub 2014 May 15. Cell Rep. 2014. PMID: 24835996 Free PMC article.

2

FoxP3 in T_reg cell biology: a molecular and structural perspective.

Deng G, Song X, Greene MI. Deng G, et al. Clin Exp Immunol. 2020 Mar;199(3):255-262. doi: 10.1111/cei.13357. Epub 2019 Sep 3. Clin Exp Immunol. 2020. PMID: 31386175 Free PMC article. Review.

3

Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells.

Deng G, Xiao Y, Zhou Z, Nagai Y, Zhang H, Li B, Greene MI. Deng G, et al. Exp Mol Pathol. 2012 Dec;93(3):334-8. doi: 10.1016/j.yexmp.2012.09.013. Epub 2012 Oct 2. Exp Mol Pathol. 2012. PMID: 23041265 Free PMC article. Review.

4

Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation.

Deng G, Nagai Y, Xiao Y, Li Z, Dai S, Ohtani T, Banham A, Li B, Wu SL, Hancock W, Samanta A, Zhang H, Greene MI. Deng G, et al. J Biol Chem. 2015 Aug 14;290(33):20211-20. doi: 10.1074/jbc.M115.638221. Epub 2015 May 18. J Biol Chem. 2015. PMID: 25987564 Free PMC article.

5

Foxp3 Post-translational Modifications and Treg Suppressive Activity.

Deng G, Song X, Fujimoto S, Piccirillo CA, Nagai Y, Greene MI. Deng G, et al. Front Immunol. 2019 Oct 18;10:2486. doi: 10.3389/fimmu.2019.02486. eCollection 2019. Front Immunol. 2019. PMID: 31681337 Free PMC article. Review.

6

A Structure-Guided Delineation of FOXP3 Regulation Mechanism in IPEX.

Ma T, Song X, Piccirillo CA, Deng G, Greene MI. Ma T, et al. Among authors: deng g. Adv Exp Med Biol. 2021;1278:33-46. doi: 10.1007/978-981-15-6407-9_2. Adv Exp Med Biol. 2021. PMID: 33523441

7

PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation.

Li Z, Lin F, Zhuo C, Deng G, Chen Z, Yin S, Gao Z, Piccioni M, Tsun A, Cai S, Zheng SG, Zhang Y, Li B. Li Z, et al. Among authors: deng g. J Biol Chem. 2014 Sep 26;289(39):26872-26881. doi: 10.1074/jbc.M114.586651. Epub 2014 Aug 5. J Biol Chem. 2014. PMID: 25096571 Free PMC article.

8

Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease.

Layman AAK, Deng G, O'Leary CE, Tadros S, Thomas RM, Dybas JM, Moser EK, Wells AD, Doliba NM, Oliver PM. Layman AAK, et al. Among authors: deng g. Nat Commun. 2017 Jun 5;8:15677. doi: 10.1038/ncomms15677. Nat Commun. 2017. PMID: 28580955 Free PMC article.

9

Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells.

O'Leary CE, Riling CR, Spruce LA, Ding H, Kumar S, Deng G, Liu Y, Seeholzer SH, Oliver PM. O'Leary CE, et al. Among authors: deng g. Nat Commun. 2016 Apr 18;7:11226. doi: 10.1038/ncomms11226. Nat Commun. 2016. PMID: 27088444 Free PMC article.

10

Ferroptosis: A Targetable Vulnerability for Melanoma Treatment.

Meng Y, Zhou Q, Dian Y, Zeng F, Deng G, Chen X. Meng Y, et al. Among authors: deng g. J Invest Dermatol. 2025 Jan 8:S0022-202X(24)03024-0. doi: 10.1016/j.jid.2024.11.007. Online ahead of print. J Invest Dermatol. 2025. PMID: 39797894 Review.

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