Giambaşu G - Search Results

1

Evidence for the role of active site residues in the hairpin ribozyme from molecular simulations along the reaction path.

Heldenbrand H, Janowski PA, Giambaşu G, Giese TJ, Wedekind JE, York DM. Heldenbrand H, et al. Among authors: giambasu g. J Am Chem Soc. 2014 Jun 4;136(22):7789-92. doi: 10.1021/ja500180q. Epub 2014 May 23. J Am Chem Soc. 2014. PMID: 24842535 Free PMC article.

2

Role of Mg2+ in hammerhead ribozyme catalysis from molecular simulation.

Lee TS, Silva López C, Giambasu GM, Martick M, Scott WG, York DM. Lee TS, et al. Among authors: giambasu gm. J Am Chem Soc. 2008 Mar 12;130(10):3053-64. doi: 10.1021/ja076529e. Epub 2008 Feb 14. J Am Chem Soc. 2008. PMID: 18271579 Free PMC article.

3

Threshold occupancy and specific cation binding modes in the hammerhead ribozyme active site are required for active conformation.

Lee TS, Giambaşu GM, Sosa CP, Martick M, Scott WG, York DM. Lee TS, et al. Among authors: giambasu gm. J Mol Biol. 2009 Apr 24;388(1):195-206. doi: 10.1016/j.jmb.2009.02.054. Epub 2009 Mar 2. J Mol Biol. 2009. PMID: 19265710 Free PMC article.

4

Predicting Site-Binding Modes of Ions and Water to Nucleic Acids Using Molecular Solvation Theory.

Giambaşu GM, Case DA, York DM. Giambaşu GM, et al. J Am Chem Soc. 2019 Feb 13;141(6):2435-2445. doi: 10.1021/jacs.8b11474. Epub 2019 Jan 29. J Am Chem Soc. 2019. PMID: 30632365 Free PMC article.

5

Characterization of the Structure and Dynamics of the HDV Ribozyme at Different Stages Along the Reaction Path.

Lee TS, Giambaşu G, Harris ME, York DM. Lee TS, et al. Among authors: giambasu g. J Phys Chem Lett. 2011 Oct 20;2(20):2538-2543. doi: 10.1021/jz201106y. J Phys Chem Lett. 2011. PMID: 22200005 Free PMC article.

6

Identification of dynamical hinge points of the L1 ligase molecular switch.

Giambasu GM, Lee TS, Sosa CP, Robertson MP, Scott WG, York DM. Giambasu GM, et al. RNA. 2010 Apr;16(4):769-80. doi: 10.1261/rna.1897810. Epub 2010 Feb 18. RNA. 2010. PMID: 20167653 Free PMC article.

7

Mapping L1 ligase ribozyme conformational switch.

Giambaşu GM, Lee TS, Scott WG, York DM. Giambaşu GM, et al. J Mol Biol. 2012 Oct 12;423(1):106-22. doi: 10.1016/j.jmb.2012.06.035. Epub 2012 Jul 3. J Mol Biol. 2012. PMID: 22771572 Free PMC article.

8

Bridging the gap between theory and experiment to derive a detailed understanding of hammerhead ribozyme catalysis.

Lee TS, Wong KY, Giambasu GM, York DM. Lee TS, et al. Prog Mol Biol Transl Sci. 2013;120:25-91. doi: 10.1016/B978-0-12-381286-5.00002-0. Prog Mol Biol Transl Sci. 2013. PMID: 24156941 Free PMC article. Review.

9

Structural fidelity and NMR relaxation analysis in a prototype RNA hairpin.

Giambaşu GM, York DM, Case DA. Giambaşu GM, et al. RNA. 2015 May;21(5):963-74. doi: 10.1261/rna.047357.114. Epub 2015 Mar 24. RNA. 2015. PMID: 25805858 Free PMC article.

10

Cation-Anion Interactions within the Nucleic Acid Ion Atmosphere Revealed by Ion Counting.

Gebala M, Giambaşu GM, Lipfert J, Bisaria N, Bonilla S, Li G, York DM, Herschlag D. Gebala M, et al. Among authors: giambasu gm. J Am Chem Soc. 2015 Nov 25;137(46):14705-15. doi: 10.1021/jacs.5b08395. Epub 2015 Nov 12. J Am Chem Soc. 2015. PMID: 26517731 Free PMC article.

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