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Use of metformin alone is not associated with survival outcomes of colorectal cancer cell but AMPK activator AICAR sensitizes anticancer effect of 5-fluorouracil through AMPK activation.
Sui X, Xu Y, Yang J, Fang Y, Lou H, Han W, Zhang M, Chen W, Wang K, Li D, Jin W, Lou F, Zheng Y, Hu H, Gong L, Zhou X, Pan Q, Pan H, Wang X, He C. Sui X, et al. Among authors: yang j. PLoS One. 2014 May 21;9(5):e97781. doi: 10.1371/journal.pone.0097781. eCollection 2014. PLoS One. 2014. PMID: 24849329 Free PMC article.
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