Jansen G - Search Results

1

Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification.

Laehnemann D, Peña-Miller R, Rosenstiel P, Beardmore R, Jansen G, Schulenburg H. Laehnemann D, et al. Among authors: jansen g. Genome Biol Evol. 2014 May 20;6(6):1287-301. doi: 10.1093/gbe/evu106. Genome Biol Evol. 2014. PMID: 24850796 Free PMC article.

2

Experimental evolution as an efficient tool to dissect adaptive paths to antibiotic resistance.

Jansen G, Barbosa C, Schulenburg H. Jansen G, et al. Drug Resist Updat. 2013 Dec;16(6):96-107. doi: 10.1016/j.drup.2014.02.002. Epub 2014 Feb 10. Drug Resist Updat. 2013. PMID: 24594007 Review.

3

Using a sequential regimen to eliminate bacteria at sublethal antibiotic dosages.

Fuentes-Hernandez A, Plucain J, Gori F, Pena-Miller R, Reding C, Jansen G, Schulenburg H, Gudelj I, Beardmore R. Fuentes-Hernandez A, et al. Among authors: jansen g. PLoS Biol. 2015 Apr 8;13(4):e1002104. doi: 10.1371/journal.pbio.1002104. eCollection 2015 Apr. PLoS Biol. 2015. PMID: 25853342 Free PMC article.

4

Evolutionary Transition from Pathogenicity to Commensalism: Global Regulator Mutations Mediate Fitness Gains through Virulence Attenuation.

Jansen G, Crummenerl LL, Gilbert F, Mohr T, Pfefferkorn R, Thänert R, Rosenstiel P, Schulenburg H. Jansen G, et al. Mol Biol Evol. 2015 Nov;32(11):2883-96. doi: 10.1093/molbev/msv160. Epub 2015 Jul 20. Mol Biol Evol. 2015. PMID: 26199376 Free PMC article.

5

Alternative Evolutionary Paths to Bacterial Antibiotic Resistance Cause Distinct Collateral Effects.

Barbosa C, Trebosc V, Kemmer C, Rosenstiel P, Beardmore R, Schulenburg H, Jansen G. Barbosa C, et al. Among authors: jansen g. Mol Biol Evol. 2017 Sep 1;34(9):2229-2244. doi: 10.1093/molbev/msx158. Mol Biol Evol. 2017. PMID: 28541480 Free PMC article.

6

Antibiotic combination efficacy (ACE) networks for a Pseudomonas aeruginosa model.

Barbosa C, Beardmore R, Schulenburg H, Jansen G. Barbosa C, et al. Among authors: jansen g. PLoS Biol. 2018 Apr 30;16(4):e2004356. doi: 10.1371/journal.pbio.2004356. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29708964 Free PMC article.

7

The Genomic Basis of Rapid Adaptation to Antibiotic Combination Therapy in Pseudomonas aeruginosa.

Barbosa C, Mahrt N, Bunk J, Graßer M, Rosenstiel P, Jansen G, Schulenburg H. Barbosa C, et al. Among authors: jansen g. Mol Biol Evol. 2021 Jan 23;38(2):449-464. doi: 10.1093/molbev/msaa233. Mol Biol Evol. 2021. PMID: 32931584 Free PMC article.

8

The Antibiotic Dosage of Fastest Resistance Evolution: Gene Amplifications Underpinning the Inverted-U.

Reding C, Catalán P, Jansen G, Bergmiller T, Wood E, Rosenstiel P, Schulenburg H, Gudelj I, Beardmore R. Reding C, et al. Among authors: jansen g. Mol Biol Evol. 2021 Aug 23;38(9):3847-3863. doi: 10.1093/molbev/msab025. Mol Biol Evol. 2021. PMID: 33693929 Free PMC article.

9

When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition.

Pena-Miller R, Laehnemann D, Jansen G, Fuentes-Hernandez A, Rosenstiel P, Schulenburg H, Beardmore R. Pena-Miller R, et al. Among authors: jansen g. PLoS Biol. 2013;11(4):e1001540. doi: 10.1371/journal.pbio.1001540. Epub 2013 Apr 23. PLoS Biol. 2013. PMID: 23630452 Free PMC article.

10

Temporal variation in antibiotic environments slows down resistance evolution in pathogenic Pseudomonas aeruginosa.

Roemhild R, Barbosa C, Beardmore RE, Jansen G, Schulenburg H. Roemhild R, et al. Among authors: jansen g. Evol Appl. 2015 Dec;8(10):945-55. doi: 10.1111/eva.12330. Epub 2015 Oct 7. Evol Appl. 2015. PMID: 26640520 Free PMC article.

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