Runyon SP - Search Results

1

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP. Thomas JB, et al. Among authors: runyon sp. J Med Chem. 2014 Jun 26;57(12):5318-32. doi: 10.1021/jm5003843. Epub 2014 Jun 5. J Med Chem. 2014. PMID: 24856674 Free PMC article.

2

Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.

Runyon SP, Savage JE, Taroua M, Roth BL, Glennon RA, Westkaemper RB. Runyon SP, et al. Bioorg Med Chem Lett. 2001 Mar 12;11(5):655-8. doi: 10.1016/s0960-894x(01)00023-3. Bioorg Med Chem Lett. 2001. PMID: 11266163

3

Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.

Runyon SP, Peddi S, Savage JE, Roth BL, Glennon RA, Westkaemper RB. Runyon SP, et al. J Med Chem. 2002 Apr 11;45(8):1656-64. doi: 10.1021/jm010354g. J Med Chem. 2002. PMID: 11931619

4

Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.

Carroll FI, Runyon SP, Abraham P, Navarro H, Kuhar MJ, Pollard GT, Howard JL. Carroll FI, et al. Among authors: runyon sp. J Med Chem. 2004 Dec 2;47(25):6401-9. doi: 10.1021/jm0401311. J Med Chem. 2004. PMID: 15566309

5

Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.

Runyon SP, Burgess JP, Abraham P, Keverline-Frantz KI, Flippen-Anderson J, Deschamps J, Lewin AH, Navarro HA, Boja JW, Kuhar MJ, Carroll FI. Runyon SP, et al. Bioorg Med Chem. 2005 Apr 1;13(7):2439-49. doi: 10.1016/j.bmc.2005.01.046. Bioorg Med Chem. 2005. PMID: 15755646

6

Dopamine transporter ligands: recent developments and therapeutic potential.

Runyon SP, Carroll FI. Runyon SP, et al. Curr Top Med Chem. 2006;6(17):1825-43. doi: 10.2174/156802606778249775. Curr Top Med Chem. 2006. PMID: 17017960 Review.

7

Identifying structural features on 1,1-diphenyl-hexahydro-oxazolo[3,4-a]pyrazin-3-ones critical for Neuropeptide S antagonist activity.

Zhang Y, Gilmour BP, Navarro HA, Runyon SP. Zhang Y, et al. Among authors: runyon sp. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4064-7. doi: 10.1016/j.bmcl.2008.05.098. Epub 2008 Jun 12. Bioorg Med Chem Lett. 2008. PMID: 18555684 Free PMC article.

8

Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation.

Runyon SP, Mosier PD, Roth BL, Glennon RA, Westkaemper RB. Runyon SP, et al. J Med Chem. 2008 Nov 13;51(21):6808-28. doi: 10.1021/jm800771x. Epub 2008 Oct 11. J Med Chem. 2008. PMID: 18847250 Free PMC article.

9

Analogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activity.

Runyon SP, Brieaddy LE, Mascarella SW, Thomas JB, Navarro HA, Howard JL, Pollard GT, Carroll FI. Runyon SP, et al. J Med Chem. 2010 Jul 22;53(14):5290-301. doi: 10.1021/jm1004978. J Med Chem. 2010. PMID: 20568781 Free PMC article.

10

1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists.

Carroll FI, Cueva JP, Thomas JB, Mascarella SW, Runyon SP, Navarro HA. Carroll FI, et al. Among authors: runyon sp. ACS Med Chem Lett. 2010 Oct 14;1(7):365-369. doi: 10.1021/ml100126b. ACS Med Chem Lett. 2010. PMID: 21116435 Free PMC article.

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