Costi MP - Search Results

1

Targeting class A and C serine β-lactamases with a broad-spectrum boronic acid derivative.

Tondi D, Venturelli A, Bonnet R, Pozzi C, Shoichet BK, Costi MP. Tondi D, et al. Among authors: costi mp. J Med Chem. 2014 Jun 26;57(12):5449-58. doi: 10.1021/jm5006572. Epub 2014 Jun 16. J Med Chem. 2014. PMID: 24882105 Free PMC article.

2

Environmental impacts of drugs against parasitic vector-borne diseases and the need to integrate sustainability into their development and use.

Lima CM, Uliassi E, Thoré ESJ, Bertram MG, Cardoso L, Cordeiro da Silva A, Costi MP, de Koning HP. Lima CM, et al. Among authors: costi mp. Open Res Eur. 2024 Nov 4;4:207. doi: 10.12688/openreseurope.18008.2. eCollection 2024. Open Res Eur. 2024. PMID: 39534878 Free PMC article.

3

Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma.

D'Arca D, Severi L, Ferrari S, Dozza L, Marverti G, Magni F, Chinello C, Pagani L, Tagliazucchi L, Villani M, d'Addese G, Piga I, Conteduca V, Rossi L, Gurioli G, De Giorgi U, Losi L, Costi MP. D'Arca D, et al. Among authors: costi mp. Cancers (Basel). 2023 Jan 8;15(2):412. doi: 10.3390/cancers15020412. Cancers (Basel). 2023. PMID: 36672361 Free PMC article.

4

Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations.

Ghelli S, Rastelli G, Barlocco D, Rinaldi M, Tondi D, Pecorari P, Costi MP. Ghelli S, et al. Among authors: costi mp. Bioorg Med Chem. 1996 Oct;4(10):1783-94. doi: 10.1016/0968-0896(96)00193-9. Bioorg Med Chem. 1996. PMID: 8931948

5

Structure-based design of inhibitors specific for bacterial thymidylate synthase.

Stout TJ, Tondi D, Rinaldi M, Barlocco D, Pecorari P, Santi DV, Kuntz ID, Stroud RM, Shoichet BK, Costi MP. Stout TJ, et al. Among authors: costi mp. Biochemistry. 1999 Feb 2;38(5):1607-17. doi: 10.1021/bi9815896. Biochemistry. 1999. PMID: 9931028

6

Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthase.

Tondi D, Slomczynska U, Costi MP, Watterson DM, Ghelli S, Shoichet BK. Tondi D, et al. Among authors: costi mp. Chem Biol. 1999 May;6(5):319-31. doi: 10.1016/S1074-5521(99)80077-5. Chem Biol. 1999. PMID: 10322126

7

Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase.

Tondi D, Powers RA, Caselli E, Negri MC, Blázquez J, Costi MP, Shoichet BK. Tondi D, et al. Among authors: costi mp. Chem Biol. 2001 Jun;8(6):593-611. doi: 10.1016/s1074-5521(01)00034-5. Chem Biol. 2001. PMID: 11410378

8

Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase.

Fritz TA, Tondi D, Finer-Moore JS, Costi MP, Stroud RM. Fritz TA, et al. Among authors: costi mp. Chem Biol. 2001 Oct;8(10):981-95. doi: 10.1016/s1074-5521(01)00067-9. Chem Biol. 2001. PMID: 11590022

9

Structure-based studies on species-specific inhibition of thymidylate synthase.

Costi MP, Tondi D, Rinaldi M, Barlocco D, Pecorari P, Soragni F, Venturelli A, Stroud RM. Costi MP, et al. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):206-14. doi: 10.1016/s0925-4439(02)00083-2. Biochim Biophys Acta. 2002. PMID: 12084462 Free article. Review.

10

Quinoxaline chemistry. Part 15. 4-[2-Quinoxalylmethylenimino]-benzoylglutamates and -benzoates, 4-[2-quinoxalylmethyl-N-methylamino]-benzoylglutamates as analogues of classical antifolate agents. Synthesis, elucidation of structures and in vitro evaluation of antifolate and anticancer activities.

Loriga M, Piras S, Paglietti G, Costi MP, Venturelli A. Loriga M, et al. Among authors: costi mp. Farmaco. 2003 Jan;58(1):51-61. doi: 10.1016/S0014-827X(02)00005-8. Farmaco. 2003. PMID: 12595037

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