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The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.
Jensen DD, Godfrey CB, Niklas C, Canals M, Kocan M, Poole DP, Murphy JE, Alemi F, Cottrell GS, Korbmacher C, Lambert NA, Bunnett NW, Corvera CU. Jensen DD, et al. Among authors: murphy je. J Biol Chem. 2013 Aug 9;288(32):22942-60. doi: 10.1074/jbc.M113.455774. Epub 2013 Jul 1. J Biol Chem. 2013. PMID: 23818521 Free PMC article.
Agonist-biased trafficking of somatostatin receptor 2A in enteric neurons.
Zhao P, Canals M, Murphy JE, Klingler D, Eriksson EM, Pelayo JC, Hardt M, Bunnett NW, Poole DP. Zhao P, et al. Among authors: murphy je. J Biol Chem. 2013 Sep 6;288(36):25689-25700. doi: 10.1074/jbc.M113.496414. Epub 2013 Aug 2. J Biol Chem. 2013. PMID: 23913690 Free PMC article.
Endosomes: a legitimate platform for the signaling train.
Murphy JE, Padilla BE, Hasdemir B, Cottrell GS, Bunnett NW. Murphy JE, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17615-22. doi: 10.1073/pnas.0906541106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822761 Free PMC article. Review.
Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor.
Murphy JE, Roosterman D, Cottrell GS, Padilla BE, Feld M, Brand E, Cedron WJ, Bunnett NW, Steinhoff M. Murphy JE, et al. Am J Physiol Cell Physiol. 2011 Oct;301(4):C780-91. doi: 10.1152/ajpcell.00096.2011. Epub 2011 Jul 27. Am J Physiol Cell Physiol. 2011. PMID: 21795521 Free PMC article.
317 results