Kassack MU - Search Results

1

Structure-Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469.

Christiansen E, Due-Hansen ME, Urban C, Merten N, Pfleiderer M, Karlsen KK, Rasmussen SS, Steensgaard M, Hamacher A, Schmidt J, Drewke C, Petersen RK, Kristiansen K, Ullrich S, Kostenis E, Kassack MU, Ulven T. Christiansen E, et al. Among authors: kassack mu. ACS Med Chem Lett. 2010 Jul 2;1(7):345-9. doi: 10.1021/ml100106c. eCollection 2010 Oct 14. ACS Med Chem Lett. 2010. PMID: 24900217 Free PMC article.

2

Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.

Ullmann H, Meis S, Hongwiset D, Marzian C, Wiese M, Nickel P, Communi D, Boeynaems JM, Wolf C, Hausmann R, Schmalzing G, Kassack MU. Ullmann H, et al. Among authors: kassack mu. J Med Chem. 2005 Nov 3;48(22):7040-8. doi: 10.1021/jm050301p. J Med Chem. 2005. PMID: 16250663

3

Dibenzazecine compounds with a novel dopamine/5HT2A receptor profile and 3D-QSAR analysis.

Hamacher A, Weigt M, Wiese M, Hoefgen B, Lehmann J, Kassack MU. Hamacher A, et al. Among authors: kassack mu. BMC Pharmacol. 2006 Sep 15;6:11. doi: 10.1186/1471-2210-6-11. BMC Pharmacol. 2006. PMID: 16978403 Free PMC article.

4

New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor.

Greve H, Meis S, Kassack MU, Kehraus S, Krick A, Wright AD, König GM. Greve H, et al. Among authors: kassack mu. J Med Chem. 2007 Nov 15;50(23):5600-7. doi: 10.1021/jm070043r. Epub 2007 Oct 17. J Med Chem. 2007. PMID: 17941622

5

Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1.

Gosepath EM, Eckstein N, Hamacher A, Servan K, von Jonquieres G, Lage H, Györffy B, Royer HD, Kassack MU. Gosepath EM, et al. Among authors: kassack mu. Int J Cancer. 2008 Nov 1;123(9):2013-9. doi: 10.1002/ijc.23721. Int J Cancer. 2008. PMID: 18688867

6

Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.

Christiansen E, Urban C, Merten N, Liebscher K, Karlsen KK, Hamacher A, Spinrath A, Bond AD, Drewke C, Ullrich S, Kassack MU, Kostenis E, Ulven T. Christiansen E, et al. Among authors: kassack mu. J Med Chem. 2008 Nov 27;51(22):7061-4. doi: 10.1021/jm8010178. J Med Chem. 2008. PMID: 18947221

7

Imidazole-based phosphane gold(I) complexes as potential agents for cancer treatment: synthesis, structural studies and antitumour activity.

Kunz PC, Kassack MU, Hamacher A, Spingler B. Kunz PC, et al. Among authors: kassack mu. Dalton Trans. 2009 Oct 7;(37):7741-7. doi: 10.1039/b902748c. Epub 2009 Jul 30. Dalton Trans. 2009. PMID: 19759948 Free article.

8

NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells.

Meis S, Hamacher A, Hongwiset D, Marzian C, Wiese M, Eckstein N, Royer HD, Communi D, Boeynaems JM, Hausmann R, Schmalzing G, Kassack MU. Meis S, et al. Among authors: kassack mu. J Pharmacol Exp Ther. 2010 Jan;332(1):238-47. doi: 10.1124/jpet.109.157750. Epub 2009 Oct 8. J Pharmacol Exp Ther. 2010. PMID: 19815812

9

Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking.

Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R. Wolf C, et al. Among authors: kassack mu. Mol Pharmacol. 2011 Apr;79(4):649-61. doi: 10.1124/mol.110.068700. Epub 2010 Dec 29. Mol Pharmacol. 2011. PMID: 21191044

10

Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.

Ebada SS, Schulz B, Wray V, Totzke F, Kubbutat MH, Müller WE, Hamacher A, Kassack MU, Lin W, Proksch P. Ebada SS, et al. Among authors: kassack mu. Bioorg Med Chem. 2011 Aug 1;19(15):4644-51. doi: 10.1016/j.bmc.2011.06.013. Epub 2011 Jul 6. Bioorg Med Chem. 2011. PMID: 21741249

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