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Probing the binding site of abl tyrosine kinase using in situ click chemistry.
Peruzzotti C, Borrelli S, Ventura M, Pantano R, Fumagalli G, Christodoulou MS, Monticelli D, Luzzani M, Fallacara AL, Tintori C, Botta M, Passarella D. Peruzzotti C, et al. Among authors: tintori c. ACS Med Chem Lett. 2013 Jan 15;4(2):274-7. doi: 10.1021/ml300394w. eCollection 2013 Feb 14. ACS Med Chem Lett. 2013. PMID: 24900659 Free PMC article.
'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.
Colombo F, Tintori C, Furlan A, Borrelli S, Christodoulou MS, Dono R, Maina F, Botta M, Amat M, Bosch J, Passarella D. Colombo F, et al. Among authors: tintori c. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4693-6. doi: 10.1016/j.bmcl.2012.05.078. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22738633
Insight into the allosteric inhibition of Abl kinase.
Fallacara AL, Tintori C, Radi M, Schenone S, Botta M. Fallacara AL, et al. Among authors: tintori c. J Chem Inf Model. 2014 May 27;54(5):1325-38. doi: 10.1021/ci500060k. Epub 2014 May 8. J Chem Inf Model. 2014. PMID: 24787133
Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.
Tintori C, Fallacara AL, Radi M, Zamperini C, Dreassi E, Crespan E, Maga G, Schenone S, Musumeci F, Brullo C, Richters A, Gasparrini F, Angelucci A, Festuccia C, Delle Monache S, Rauh D, Botta M. Tintori C, et al. J Med Chem. 2015 Jan 8;58(1):347-61. doi: 10.1021/jm5013159. Epub 2014 Dec 3. J Med Chem. 2015. PMID: 25469771
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors.
Tintori C, La Sala G, Vignaroli G, Botta L, Fallacara AL, Falchi F, Radi M, Zamperini C, Dreassi E, Dello Iacono L, Orioli D, Biamonti G, Garbelli M, Lossani A, Gasparrini F, Tuccinardi T, Laurenzana I, Angelucci A, Maga G, Schenone S, Brullo C, Musumeci F, Desogus A, Crespan E, Botta M. Tintori C, et al. J Med Chem. 2015 Jun 11;58(11):4590-609. doi: 10.1021/acs.jmedchem.5b00140. Epub 2015 May 20. J Med Chem. 2015. PMID: 25923950
55 results