Dornan GL - Search Results

1

The genetic and biochemical basis of FANCD2 monoubiquitination.

Rajendra E, Oestergaard VH, Langevin F, Wang M, Dornan GL, Patel KJ, Passmore LA. Rajendra E, et al. Among authors: dornan gl. Mol Cell. 2014 Jun 5;54(5):858-69. doi: 10.1016/j.molcel.2014.05.001. Mol Cell. 2014. PMID: 24905007 Free PMC article.

2

Architecture of eukaryotic mRNA 3'-end processing machinery.

Casañal A, Kumar A, Hill CH, Easter AD, Emsley P, Degliesposti G, Gordiyenko Y, Santhanam B, Wolf J, Wiederhold K, Dornan GL, Skehel M, Robinson CV, Passmore LA. Casañal A, et al. Among authors: dornan gl. Science. 2017 Nov 24;358(6366):1056-1059. doi: 10.1126/science.aao6535. Epub 2017 Oct 26. Science. 2017. PMID: 29074584 Free PMC article.

3

Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex.

Dornan GL, Dalwadi U, Hamelin DJ, Hoffmann RM, Yip CK, Burke JE. Dornan GL, et al. J Mol Biol. 2018 Sep 14;430(18 Pt B):3129-3142. doi: 10.1016/j.jmb.2018.07.020. Epub 2018 Jul 18. J Mol Biol. 2018. PMID: 30031006

4

Type III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease.

Dornan GL, McPhail JA, Burke JE. Dornan GL, et al. Biochem Soc Trans. 2016 Feb;44(1):260-6. doi: 10.1042/BST20150219. Biochem Soc Trans. 2016. PMID: 26862213 Review.

5

Using Hydrogen-Deuterium Exchange Mass Spectrometry to Examine Protein-Membrane Interactions.

Vadas O, Jenkins ML, Dornan GL, Burke JE. Vadas O, et al. Among authors: dornan gl. Methods Enzymol. 2017;583:143-172. doi: 10.1016/bs.mie.2016.09.008. Epub 2016 Oct 18. Methods Enzymol. 2017. PMID: 28063489 Review.

6

Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases.

Dornan GL, Burke JE. Dornan GL, et al. Front Immunol. 2018 Mar 19;9:575. doi: 10.3389/fimmu.2018.00575. eCollection 2018. Front Immunol. 2018. PMID: 29616047 Free PMC article. Review.

7

Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases.

Dornan GL, Stariha JTB, Rathinaswamy MK, Powell CJ, Boulanger MJ, Burke JE. Dornan GL, et al. Structure. 2020 Feb 4;28(2):145-156.e5. doi: 10.1016/j.str.2019.11.013. Epub 2019 Dec 9. Structure. 2020. PMID: 31831213 Free article.

8

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

Dornan GL, Siempelkamp BD, Jenkins ML, Vadas O, Lucas CL, Burke JE. Dornan GL, et al. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1982-1987. doi: 10.1073/pnas.1617244114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167755 Free PMC article.

9

Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ.

Rutaganira FU, Fowler ML, McPhail JA, Gelman MA, Nguyen K, Xiong A, Dornan GL, Tavshanjian B, Glenn JS, Shokat KM, Burke JE. Rutaganira FU, et al. Among authors: dornan gl. J Med Chem. 2016 Mar 10;59(5):1830-9. doi: 10.1021/acs.jmedchem.5b01311. Epub 2016 Feb 26. J Med Chem. 2016. PMID: 26885694 Free PMC article.

10

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans.

Takeda AJ, Zhang Y, Dornan GL, Siempelkamp BD, Jenkins ML, Matthews HF, McElwee JJ, Bi W, Seeborg FO, Su HC, Burke JE, Lucas CL. Takeda AJ, et al. Among authors: dornan gl. J Allergy Clin Immunol. 2017 Oct;140(4):1152-1156.e10. doi: 10.1016/j.jaci.2017.03.026. Epub 2017 Apr 13. J Allergy Clin Immunol. 2017. PMID: 28414062 Free PMC article. No abstract available.

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