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Page 1
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.
Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, Chen Z, Francek C, Wu T, Nagle A, Barnes SW, Plouffe D, Lee MC, Fidock DA, Graumans W, van de Vegte-Bolmer M, van Gemert GJ, Wirjanata G, Sebayang B, Marfurt J, Russell B, Suwanarusk R, Price RN, Nosten F, Tungtaeng A, Gettayacamin M, Sattabongkot J, Taylor J, Walker JR, Tully D, Patra KP, Flannery EL, Vinetz JM, Renia L, Sauerwein RW, Winzeler EA, Glynne RJ, Diagana TT. Kuhen KL, et al. Among authors: van de vegte bolmer m, van gemert gj. Antimicrob Agents Chemother. 2014 Sep;58(9):5060-7. doi: 10.1128/AAC.02727-13. Epub 2014 Jun 9. Antimicrob Agents Chemother. 2014. PMID: 24913172 Free PMC article.
Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins.
Proellochs NI, Andolina C, Ramjith J, Stoter R, van Gemert GJ, Graumans W, Campino S, Vanheer LN, Okitwi M, Tumwebaze PK, Conrad MD, Clark TG, Fidock DA, Menard D, Mok S, Bousema T. Proellochs NI, et al. Among authors: van gemert gj. bioRxiv [Preprint]. 2024 Dec 23:2024.12.23.630038. doi: 10.1101/2024.12.23.630038. bioRxiv. 2024. PMID: 39763803 Free PMC article. Preprint.
Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite.
Lamers OAC, Franke-Fayard BMD, Koopman JPR, Roozen GVT, Janse JJ, Chevalley-Maurel SC, Geurten FJA, de Bes-Roeleveld HM, Iliopoulou E, Colstrup E, Wessels E, van Gemert GJ, van de Vegte-Bolmer M, Graumans W, Stoter TR, Mordmüller BG, Houlder EL, Bousema T, Murugan R, McCall MBB, Janse CJ, Roestenberg M. Lamers OAC, et al. Among authors: van gemert gj. N Engl J Med. 2024 Nov 21;391(20):1913-1923. doi: 10.1056/NEJMoa2313892. N Engl J Med. 2024. PMID: 39565990 Clinical Trial.
Detailing organelle division and segregation in Plasmodium falciparum.
Verhoef JMJ, Boshoven C, Evers F, Akkerman LJ, Gijsbrechts BCA, van de Vegte-Bolmer M, van Gemert GJ, Vaidya AB, Kooij TWA. Verhoef JMJ, et al. Among authors: van gemert gj. J Cell Biol. 2024 Dec 2;223(12):e202406064. doi: 10.1083/jcb.202406064. Epub 2024 Nov 1. J Cell Biol. 2024. PMID: 39485315
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.
Alkema M, Smit MJ, Marin-Mogollon C, Totté K, Teelen K, van Gemert GJ, van de Vegte-Bolmer M, Mordmüller BG, Reimer JM, Lövgren-Bengtsson KL, Sauerwein RW, Bousema T, Plieskatt J, Theisen M, Jore MM, McCall MBB. Alkema M, et al. Among authors: van gemert gj. BMC Med. 2024 Apr 23;22(1):170. doi: 10.1186/s12916-024-03379-y. BMC Med. 2024. PMID: 38649867 Free PMC article. Clinical Trial.
Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes.
Andolina C, Graumans W, Guelbeogo M, van Gemert GJ, Ramijth J, Harouna S, Soumanaba Z, Stoter R, Vegte-Bolmer M, Pangos M, Sinnis P, Collins K, Staedke SG, Tiono AB, Drakeley C, Lanke K, Bousema T. Andolina C, et al. Among authors: van gemert gj. Elife. 2024 Mar 22;12:RP90989. doi: 10.7554/eLife.90989. Elife. 2024. PMID: 38517746 Free PMC article.
Detailing organelle division and segregation in Plasmodium falciparum.
Verhoef JMJ, Boshoven C, Evers F, Akkerman LJ, Gijsbrechts BCA, van de Vegte-Bolmer M, van Gemert GJ, Vaidya AB, Kooij TWA. Verhoef JMJ, et al. Among authors: van gemert gj. bioRxiv [Preprint]. 2024 May 13:2024.01.30.577899. doi: 10.1101/2024.01.30.577899. bioRxiv. 2024. Update in: J Cell Biol. 2024 Dec 2;223(12):e202406064. doi: 10.1083/jcb.202406064 PMID: 38352445 Free PMC article. Updated. Preprint.
Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibody.
Inklaar MR, de Jong RM, Bekkering ET, Nagaoka H, Fennemann FL, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Stoter R, King CR, Proellochs NI, Bousema T, Takashima E, Tsuboi T, Jore MM. Inklaar MR, et al. Among authors: van gemert gj. NPJ Vaccines. 2023 Dec 12;8(1):186. doi: 10.1038/s41541-023-00784-x. NPJ Vaccines. 2023. PMID: 38086855 Free PMC article.
135 results