Taylor JP - Search Results

1

TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.

He F, Krans A, Freibaum BD, Taylor JP, Todd PK. He F, et al. Among authors: taylor jp. Hum Mol Genet. 2014 Oct 1;23(19):5036-51. doi: 10.1093/hmg/ddu216. Epub 2014 May 8. Hum Mol Genet. 2014. PMID: 24920338 Free PMC article.

2

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection.

Nedelsky NB, Todd PK, Taylor JP. Nedelsky NB, et al. Among authors: taylor jp. Biochim Biophys Acta. 2008 Dec;1782(12):691-9. doi: 10.1016/j.bbadis.2008.10.002. Epub 2008 Oct 10. Biochim Biophys Acta. 2008. PMID: 18930136 Free PMC article. Review.

3

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

Freibaum BD, Chitta RK, High AA, Taylor JP. Freibaum BD, et al. Among authors: taylor jp. J Proteome Res. 2010 Feb 5;9(2):1104-20. doi: 10.1021/pr901076y. J Proteome Res. 2010. PMID: 20020773 Free PMC article.

4

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation.

McCray BA, Skordalakes E, Taylor JP. McCray BA, et al. Among authors: taylor jp. Hum Mol Genet. 2010 Mar 15;19(6):1033-47. doi: 10.1093/hmg/ddp567. Epub 2009 Dec 22. Hum Mol Genet. 2010. PMID: 20028791 Free PMC article.

5

Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.

Custer SK, Neumann M, Lu H, Wright AC, Taylor JP. Custer SK, et al. Among authors: taylor jp. Hum Mol Genet. 2010 May 1;19(9):1741-55. doi: 10.1093/hmg/ddq050. Epub 2010 Feb 10. Hum Mol Genet. 2010. PMID: 20147319 Free article.

6

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

Ritson GP, Custer SK, Freibaum BD, Guinto JB, Geffel D, Moore J, Tang W, Winton MJ, Neumann M, Trojanowski JQ, Lee VM, Forman MS, Taylor JP. Ritson GP, et al. Among authors: taylor jp. J Neurosci. 2010 Jun 2;30(22):7729-39. doi: 10.1523/JNEUROSCI.5894-09.2010. J Neurosci. 2010. PMID: 20519548 Free PMC article.

7

Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.

Todd PK, Oh SY, Krans A, Pandey UB, Di Prospero NA, Min KT, Taylor JP, Paulson HL. Todd PK, et al. Among authors: taylor jp. PLoS Genet. 2010 Dec 9;6(12):e1001240. doi: 10.1371/journal.pgen.1001240. PLoS Genet. 2010. PMID: 21170301 Free PMC article.

8

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.

Lanson NA Jr, Maltare A, King H, Smith R, Kim JH, Taylor JP, Lloyd TE, Pandey UB. Lanson NA Jr, et al. Among authors: taylor jp. Hum Mol Genet. 2011 Jul 1;20(13):2510-23. doi: 10.1093/hmg/ddr150. Epub 2011 Apr 12. Hum Mol Genet. 2011. PMID: 21487023 Free PMC article.

9

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.

Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP. Kim HJ, et al. Among authors: taylor jp. Nature. 2013 Mar 28;495(7442):467-73. doi: 10.1038/nature11922. Epub 2013 Mar 3. Nature. 2013. PMID: 23455423 Free PMC article.

10

CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.

Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, Mills RE, Charlet-Berguerand N, Paulson HL. Todd PK, et al. Among authors: taylor jp. Neuron. 2013 May 8;78(3):440-55. doi: 10.1016/j.neuron.2013.03.026. Epub 2013 Apr 18. Neuron. 2013. PMID: 23602499 Free PMC article.

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