Xu J - Search Results

1

Germline mutation of Bap1 accelerates development of asbestos-induced malignant mesothelioma.

Xu J, Kadariya Y, Cheung M, Pei J, Talarchek J, Sementino E, Tan Y, Menges CW, Cai KQ, Litwin S, Peng H, Karar J, Rauscher FJ, Testa JR. Xu J, et al. Cancer Res. 2014 Aug 15;74(16):4388-97. doi: 10.1158/0008-5472.CAN-14-1328. Epub 2014 Jun 13. Cancer Res. 2014. PMID: 24928783 Free PMC article.

2

A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.

Tan Y, Timakhov RA, Rao M, Altomare DA, Xu J, Liu Z, Gao Q, Jhanwar SC, Di Cristofano A, Wiest DL, Knepper JE, Testa JR. Tan Y, et al. Among authors: xu j. Cancer Res. 2008 Mar 1;68(5):1296-302. doi: 10.1158/0008-5472.CAN-07-3218. Cancer Res. 2008. PMID: 18316591

3

DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYC.

Xu J, Testa JR. Xu J, et al. J Biol Chem. 2009 Jul 31;284(31):20593-601. doi: 10.1074/jbc.M109.021477. Epub 2009 Jun 4. J Biol Chem. 2009. PMID: 19497851 Free PMC article.

4

Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.

Altomare DA, Menges CW, Xu J, Pei J, Zhang L, Tadevosyan A, Neumann-Domer E, Liu Z, Carbone M, Chudoba I, Klein-Szanto AJ, Testa JR. Altomare DA, et al. Among authors: xu j. PLoS One. 2011 Apr 19;6(4):e18828. doi: 10.1371/journal.pone.0018828. PLoS One. 2011. PMID: 21526190 Free PMC article.

5

Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.

Menges CW, Sementino E, Talarchek J, Xu J, Chernoff J, Peterson JR, Testa JR. Menges CW, et al. Among authors: xu j. Mol Cancer Res. 2012 Sep;10(9):1178-88. doi: 10.1158/1541-7786.MCR-12-0082. Epub 2012 Jul 12. Mol Cancer Res. 2012. PMID: 22798428 Free PMC article.

6

Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations.

Kadariya Y, Cheung M, Xu J, Pei J, Sementino E, Menges CW, Cai KQ, Rauscher FJ, Klein-Szanto AJ, Testa JR. Kadariya Y, et al. Among authors: xu j. Cancer Res. 2016 May 1;76(9):2836-44. doi: 10.1158/0008-5472.CAN-15-3371. Epub 2016 Feb 19. Cancer Res. 2016. PMID: 26896281 Free PMC article.

7

The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling.

Tan Y, Sementino E, Xu J, Pei J, Liu Z, Ito TK, Cai KQ, Peri S, Klein-Szanto AJ, Wiest DL, Testa JR. Tan Y, et al. Among authors: xu j. Oncotarget. 2017 Feb 28;8(9):14941-14956. doi: 10.18632/oncotarget.14784. Oncotarget. 2017. PMID: 28122332 Free PMC article.

8

Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas.

Sementino E, Menges CW, Kadariya Y, Peri S, Xu J, Liu Z, Wilkes RG, Cai KQ, Rauscher FJ 3rd, Klein-Szanto AJ, Testa JR. Sementino E, et al. Among authors: xu j. J Cell Physiol. 2018 Nov;233(11):8952-8961. doi: 10.1002/jcp.26830. Epub 2018 Jun 15. J Cell Physiol. 2018. PMID: 29904909 Free PMC article.

9

Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis.

Gary JM, Simmons JK, Xu J, Zhang S, Peat TJ, Watson N, Gamache BJ, Zhang K, Kovalchuk AL, Michalowski AM, Chen JQ, Thaiwong T, Kiupel M, Gaikwad S, Etienne M, Simpson RM, Dubois W, Testa JR, Mock BA. Gary JM, et al. Among authors: xu j. Mol Cancer Ther. 2020 Oct;19(10):2221-2232. doi: 10.1158/1535-7163.MCT-19-0671. Epub 2020 Aug 3. Mol Cancer Ther. 2020. PMID: 32747423 Free PMC article.

10

TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.

Tricarico R, Madzo J, Scher G, Cohen M, Jelinek J, Maegawa S, Nagarathinam R, Scher C, Chang WC, Nicolas E, Slifker M, Zhou Y, Devarajan K, Cai KQ, Kwok T, Nakajima P, Xu J, Mancuso P, Doneddu V, Bagella L, Williams R, Balachandran S, Maskalenko N, Campbell K, Ma X, Cañadas I, Viana-Errasti J, Moreno V, Valle L, Grivennikov S, Peshkova I, Kurilenko N, Mazitova A, Koltsova E, Lee H, Walsh M, Duttweiler R, Whetstine JR, Yen TJ, Issa JP, Bellacosa A. Tricarico R, et al. Among authors: xu j. Gastroenterology. 2023 May;164(6):921-936.e1. doi: 10.1053/j.gastro.2023.01.039. Epub 2023 Feb 8. Gastroenterology. 2023. PMID: 36764492 Free PMC article.

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