Grubisha O - Search Results

1

Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.

Ursu D, Ebert P, Langron E, Ruble C, Munsie L, Zou W, Fijal B, Qian YW, McNearney TA, Mogg A, Grubisha O, Merchant K, Sher E. Ursu D, et al. Among authors: grubisha o. Mol Pain. 2014 Jun 16;10:37. doi: 10.1186/1744-8069-10-37. Mol Pain. 2014. PMID: 24934217 Free PMC article.

2

Pharmacological profiling of the TRPV3 channel in recombinant and native assays.

Grubisha O, Mogg AJ, Sorge JL, Ball LJ, Sanger H, Ruble CL, Folly EA, Ursu D, Broad LM. Grubisha O, et al. Br J Pharmacol. 2014 May;171(10):2631-44. doi: 10.1111/bph.12303. Br J Pharmacol. 2014. PMID: 23848361 Free PMC article.

3

Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR.

Sanger H, Hanna L, Colvin EM, Grubisha O, Ursu D, Heinz BA, Findlay JD, Vivier RG, Sher E, Lodge D, Monn JA, Broad LM. Sanger H, et al. Among authors: grubisha o. Neuropharmacology. 2013 Mar;66:264-73. doi: 10.1016/j.neuropharm.2012.05.023. Epub 2012 May 30. Neuropharmacology. 2013. PMID: 22659090

4

Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation.

Mazzo F, Butnaru I, Grubisha O, Ficulle E, Sanger H, Fitzgerald G, Pan F, Pasqui F, Murray T, Monn J, Li X, Hutton M, Bose S, Schiavo G, Sher E. Mazzo F, et al. Among authors: grubisha o. J Pharmacol Exp Ther. 2022 Nov;383(2):117-128. doi: 10.1124/jpet.122.001307. Epub 2022 Sep 18. J Pharmacol Exp Ther. 2022. PMID: 36116796

5

Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a.

Hufgard JR, Williams MT, Skelton MR, Grubisha O, Ferreira FM, Sanger H, Wright ME, Reed-Kessler TM, Rasmussen K, Duman RS, Vorhees CV. Hufgard JR, et al. Among authors: grubisha o. Psychopharmacology (Berl). 2017 Jun;234(12):1803-1813. doi: 10.1007/s00213-017-4587-8. Epub 2017 Mar 23. Psychopharmacology (Berl). 2017. PMID: 28337525

6

Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity.

Collins R, Lee H, Jones DH, Elkins JM, Gillespie JA, Thomas C, Baldwin AG, Jones K, Waters L, Paine M, Atack JR, Ward SE, Grubisha O, Foley DW. Collins R, et al. Among authors: grubisha o. J Med Chem. 2022 Oct 27;65(20):13705-13713. doi: 10.1021/acs.jmedchem.2c00751. Epub 2022 Oct 7. J Med Chem. 2022. PMID: 36205722 Free PMC article.

7

A toolkit for the identification of NEAT1_2/paraspeckle modulators.

An H, Elvers KT, Gillespie JA, Jones K, Atack JR, Grubisha O, Shelkovnikova TA. An H, et al. Among authors: grubisha o. Nucleic Acids Res. 2022 Nov 11;50(20):e119. doi: 10.1093/nar/gkac771. Nucleic Acids Res. 2022. PMID: 36099417 Free PMC article.

8

Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.

Koulouris CR, Gardiner SE, Harris TK, Elvers KT, Mark Roe S, Gillespie JA, Ward SE, Grubisha O, Nicholls RA, Atack JR, Bax BD. Koulouris CR, et al. Among authors: grubisha o. Commun Biol. 2022 Apr 11;5(1):346. doi: 10.1038/s42003-022-03264-5. Commun Biol. 2022. PMID: 35410329 Free PMC article.

9

DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.

Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israël A, Véron M, Agou F. Grubisha O, et al. J Mol Biol. 2010 Jan 8;395(1):89-104. doi: 10.1016/j.jmb.2009.10.018. Epub 2009 Oct 23. J Mol Biol. 2010. PMID: 19854204

10

The zinc finger of NEMO is a functional ubiquitin-binding domain.

Cordier F, Grubisha O, Traincard F, Véron M, Delepierre M, Agou F. Cordier F, et al. Among authors: grubisha o. J Biol Chem. 2009 Jan 30;284(5):2902-2907. doi: 10.1074/jbc.M806655200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033441 Free article.

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