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3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease.
Sagong HY, Parhi A, Bauman JD, Patel D, Vijayan RS, Das K, Arnold E, LaVoie EJ. Sagong HY, et al. Among authors: arnold e. ACS Med Chem Lett. 2013 May 7;4(6):547-50. doi: 10.1021/ml4001112. eCollection 2013 Jun 13. ACS Med Chem Lett. 2013. PMID: 24936242 Free PMC article.
Structural basis of BLyS receptor recognition.
Oren DA, Li Y, Volovik Y, Morris TS, Dharia C, Das K, Galperina O, Gentz R, Arnold E. Oren DA, et al. Among authors: arnold e. Nat Struct Biol. 2002 Apr;9(4):288-92. doi: 10.1038/nsb769. Nat Struct Biol. 2002. PMID: 11862220
Trapping HIV-1 reverse transcriptase before and after translocation on DNA.
Sarafianos SG, Clark AD Jr, Tuske S, Squire CJ, Das K, Sheng D, Ilankumaran P, Ramesha AR, Kroth H, Sayer JM, Jerina DM, Boyer PL, Hughes SH, Arnold E. Sarafianos SG, et al. Among authors: arnold e. J Biol Chem. 2003 May 2;278(18):16280-8. doi: 10.1074/jbc.M212911200. Epub 2003 Jan 28. J Biol Chem. 2003. PMID: 12554739 Free article.
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.
Das K, Clark AD Jr, Lewi PJ, Heeres J, De Jonge MR, Koymans LM, Vinkers HM, Daeyaert F, Ludovici DW, Kukla MJ, De Corte B, Kavash RW, Ho CY, Ye H, Lichtenstein MA, Andries K, Pauwels R, De Béthune MP, Boyer PL, Clark P, Hughes SH, Janssen PA, Arnold E. Das K, et al. Among authors: arnold e. J Med Chem. 2004 May 6;47(10):2550-60. doi: 10.1021/jm030558s. J Med Chem. 2004. PMID: 15115397
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
Heeres J, de Jonge MR, Koymans LM, Daeyaert FF, Vinkers M, Van Aken KJ, Arnold E, Das K, Kilonda A, Hoornaert GJ, Compernolle F, Cegla M, Azzam RA, Andries K, de Béthune MP, Azijn H, Pauwels R, Lewi PJ, Janssen PA. Heeres J, et al. Among authors: arnold e. J Med Chem. 2005 Mar 24;48(6):1910-8. doi: 10.1021/jm040829e. J Med Chem. 2005. PMID: 15771435
953 results