Bacos K - Search Results

1

Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.

Hall E, Volkov P, Dayeh T, Bacos K, Rönn T, Nitert MD, Ling C. Hall E, et al. Among authors: bacos k. BMC Med. 2014 Jun 23;12:103. doi: 10.1186/1741-7015-12-103. BMC Med. 2014. PMID: 24953961 Free PMC article.

2

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.

Malmgren S, Nicholls DG, Taneera J, Bacos K, Koeck T, Tamaddon A, Wibom R, Groop L, Ling C, Mulder H, Sharoyko VV. Malmgren S, et al. Among authors: bacos k. J Biol Chem. 2009 Nov 20;284(47):32395-404. doi: 10.1074/jbc.M109.026708. Epub 2009 Sep 21. J Biol Chem. 2009. PMID: 19797055 Free PMC article.

3

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

Dayeh T, Volkov P, Salö S, Hall E, Nilsson E, Olsson AH, Kirkpatrick CL, Wollheim CB, Eliasson L, Rönn T, Bacos K, Ling C. Dayeh T, et al. Among authors: bacos k. PLoS Genet. 2014 Mar 6;10(3):e1004160. doi: 10.1371/journal.pgen.1004160. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24603685 Free PMC article.

4

Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.

Olsson AH, Volkov P, Bacos K, Dayeh T, Hall E, Nilsson EA, Ladenvall C, Rönn T, Ling C. Olsson AH, et al. Among authors: bacos k. PLoS Genet. 2014 Nov 6;10(11):e1004735. doi: 10.1371/journal.pgen.1004735. eCollection 2014 Nov. PLoS Genet. 2014. PMID: 25375650 Free PMC article.

5

Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets.

Hall E, Volkov P, Dayeh T, Esguerra JL, Salö S, Eliasson L, Rönn T, Bacos K, Ling C. Hall E, et al. Among authors: bacos k. Genome Biol. 2014 Dec 3;15(12):522. doi: 10.1186/s13059-014-0522-z. Genome Biol. 2014. PMID: 25517766 Free PMC article.

6

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.

Bacos K, Gillberg L, Volkov P, Olsson AH, Hansen T, Pedersen O, Gjesing AP, Eiberg H, Tuomi T, Almgren P, Groop L, Eliasson L, Vaag A, Dayeh T, Ling C. Bacos K, et al. Nat Commun. 2016 Mar 31;7:11089. doi: 10.1038/ncomms11089. Nat Commun. 2016. PMID: 27029739 Free PMC article.

7

HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells.

Daneshpajooh M, Bacos K, Bysani M, Bagge A, Ottosson Laakso E, Vikman P, Eliasson L, Mulder H, Ling C. Daneshpajooh M, et al. Among authors: bacos k. Diabetologia. 2017 Jan;60(1):116-125. doi: 10.1007/s00125-016-4113-2. Epub 2016 Oct 29. Diabetologia. 2017. PMID: 27796421 Free PMC article.

8

Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis.

Volkov P, Bacos K, Ofori JK, Esguerra JL, Eliasson L, Rönn T, Ling C. Volkov P, et al. Among authors: bacos k. Diabetes. 2017 Apr;66(4):1074-1085. doi: 10.2337/db16-0996. Epub 2017 Jan 4. Diabetes. 2017. PMID: 28052964

9

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.

Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, Klös M, Bacos K, Kern M, Eichelmann F, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll M, Kovacs P, DiBlasio AM, Ling C, Binder H, Blüher M, Böttcher Y. Keller M, et al. Among authors: bacos k. Mol Metab. 2016 Nov 16;6(1):86-100. doi: 10.1016/j.molmet.2016.11.003. eCollection 2017 Jan. Mol Metab. 2016. PMID: 28123940 Free PMC article.

10

Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function.

Backe MB, Andersson JL, Bacos K, Christensen DP, Hansen JB, Dorosz JJ, Gajhede M, Dahlby T, Bysani M, Kristensen LH, Ling C, Olsen L, Mandrup-Poulsen T. Backe MB, et al. Among authors: bacos k. Mol Cell Endocrinol. 2018 Jan 15;460:47-56. doi: 10.1016/j.mce.2017.07.001. Epub 2017 Jul 4. Mol Cell Endocrinol. 2018. PMID: 28684291

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