Koo MS - Search Results

1

Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.

Nixon MR, Saionz KW, Koo MS, Szymonifka MJ, Jung H, Roberts JP, Nandakumar M, Kumar A, Liao R, Rustad T, Sacchettini JC, Rhee KY, Freundlich JS, Sherman DR. Nixon MR, et al. Among authors: koo ms. Chem Biol. 2014 Jul 17;21(7):819-30. doi: 10.1016/j.chembiol.2014.04.009. Epub 2014 Jun 19. Chem Biol. 2014. PMID: 24954008

2

Bayesian models leveraging bioactivity and cytotoxicity information for drug discovery.

Ekins S, Reynolds RC, Kim H, Koo MS, Ekonomidis M, Talaue M, Paget SD, Woolhiser LK, Lenaerts AJ, Bunin BA, Connell N, Freundlich JS. Ekins S, et al. Among authors: koo ms. Chem Biol. 2013 Mar 21;20(3):370-8. doi: 10.1016/j.chembiol.2013.01.011. Chem Biol. 2013. PMID: 23521795 Free PMC article.

3

Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection.

Manca C, Koo MS, Peixoto B, Fallows D, Kaplan G, Subbian S. Manca C, et al. Among authors: koo ms. PLoS One. 2013 Aug 28;8(8):e74082. doi: 10.1371/journal.pone.0074082. eCollection 2013. PLoS One. 2013. PMID: 24015316 Free PMC article.

4

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs.

Subbian S, Tsenova L, O'Brien P, Yang G, Koo MS, Peixoto B, Fallows D, Dartois V, Muller G, Kaplan G. Subbian S, et al. Among authors: koo ms. PLoS Pathog. 2011 Sep;7(9):e1002262. doi: 10.1371/journal.ppat.1002262. Epub 2011 Sep 15. PLoS Pathog. 2011. PMID: 21949656 Free PMC article.

5

Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.

Koo MS, Manca C, Yang G, O'Brien P, Sung N, Tsenova L, Subbian S, Fallows D, Muller G, Ehrt S, Kaplan G. Koo MS, et al. PLoS One. 2011 Feb 25;6(2):e17091. doi: 10.1371/journal.pone.0017091. PLoS One. 2011. PMID: 21364878 Free PMC article.

6

Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology.

Subbian S, Tsenova L, O'Brien P, Yang G, Koo MS, Peixoto B, Fallows D, Zeldis JB, Muller G, Kaplan G. Subbian S, et al. Among authors: koo ms. Am J Pathol. 2011 Jul;179(1):289-301. doi: 10.1016/j.ajpath.2011.03.039. Epub 2011 May 7. Am J Pathol. 2011. PMID: 21703411 Free PMC article.

7

Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis.

Subbian S, Koo MS, Tsenova L, Khetani V, Zeldis JB, Fallows D, Kaplan G. Subbian S, et al. Among authors: koo ms. Front Immunol. 2016 Jun 17;7:238. doi: 10.3389/fimmu.2016.00238. eCollection 2016. Front Immunol. 2016. PMID: 27379099 Free PMC article.

8

The phenolic glycolipid of Mycobacterium tuberculosis differentially modulates the early host cytokine response but does not in itself confer hypervirulence.

Sinsimer D, Huet G, Manca C, Tsenova L, Koo MS, Kurepina N, Kana B, Mathema B, Marras SA, Kreiswirth BN, Guilhot C, Kaplan G. Sinsimer D, et al. Among authors: koo ms. Infect Immun. 2008 Jul;76(7):3027-36. doi: 10.1128/IAI.01663-07. Epub 2008 Apr 28. Infect Immun. 2008. PMID: 18443098 Free PMC article.

9

Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis.

Das R, Koo MS, Kim BH, Jacob ST, Subbian S, Yao J, Leng L, Levy R, Murchison C, Burman WJ, Moore CC, Scheld WM, David JR, Kaplan G, MacMicking JD, Bucala R. Das R, et al. Among authors: koo ms. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2997-3006. doi: 10.1073/pnas.1301128110. Epub 2013 Jul 23. Proc Natl Acad Sci U S A. 2013. PMID: 23882081 Free PMC article.

10

Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling.

Qualls JE, Neale G, Smith AM, Koo MS, DeFreitas AA, Zhang H, Kaplan G, Watowich SS, Murray PJ. Qualls JE, et al. Among authors: koo ms. Sci Signal. 2010 Aug 17;3(135):ra62. doi: 10.1126/scisignal.2000955. Sci Signal. 2010. PMID: 20716764 Free PMC article.

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