Rhee KY - Search Results

1

Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.

Nixon MR, Saionz KW, Koo MS, Szymonifka MJ, Jung H, Roberts JP, Nandakumar M, Kumar A, Liao R, Rustad T, Sacchettini JC, Rhee KY, Freundlich JS, Sherman DR. Nixon MR, et al. Among authors: rhee ky. Chem Biol. 2014 Jul 17;21(7):819-30. doi: 10.1016/j.chembiol.2014.04.009. Epub 2014 Jun 19. Chem Biol. 2014. PMID: 24954008

2

Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.

de Carvalho LP, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee KY. de Carvalho LP, et al. Among authors: rhee ky. Chem Biol. 2010 Apr 23;17(4):323-32. doi: 10.1016/j.chembiol.2010.03.009. Chem Biol. 2010. PMID: 20416504 Free PMC article.

3

Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.

de Carvalho LP, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY. de Carvalho LP, et al. Among authors: rhee ky. Chem Biol. 2010 Oct 29;17(10):1122-31. doi: 10.1016/j.chembiol.2010.08.009. Chem Biol. 2010. PMID: 21035735

4

Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.

de Carvalho LP, Darby CM, Rhee KY, Nathan C. de Carvalho LP, et al. Among authors: rhee ky. ACS Med Chem Lett. 2011;2(11):849-854. doi: 10.1021/ml200157f. ACS Med Chem Lett. 2011. PMID: 22096616 Free PMC article.

5

Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis.

Chakraborty S, Gruber T, Barry CE 3rd, Boshoff HI, Rhee KY. Chakraborty S, et al. Among authors: rhee ky. Science. 2013 Jan 4;339(6115):88-91. doi: 10.1126/science.1228980. Epub 2012 Nov 1. Science. 2013. PMID: 23118010 Free PMC article.

6

Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis.

Nandakumar M, Nathan C, Rhee KY. Nandakumar M, et al. Among authors: rhee ky. Nat Commun. 2014 Jun 30;5:4306. doi: 10.1038/ncomms5306. Nat Commun. 2014. PMID: 24978671 Free article.

7

Metabolomics of Mycobacterium tuberculosis.

Nandakumar M, Prosser GA, de Carvalho LP, Rhee K. Nandakumar M, et al. Methods Mol Biol. 2015;1285:105-15. doi: 10.1007/978-1-4939-2450-9_6. Methods Mol Biol. 2015. PMID: 25779312

8

Evolution of a thienopyrimidine antitubercular relying on medicinal chemistry and metabolomics insights.

Li SG, Vilchèze C, Chakraborty S, Wang X, Kim H, Anisetti M, Ekins S, Rhee KY, Jacobs WR Jr, Freundlich JS. Li SG, et al. Among authors: rhee ky. Tetrahedron Lett. 2015 Jun 3;56(23):3246-3250. doi: 10.1016/j.tetlet.2015.02.129. Tetrahedron Lett. 2015. PMID: 26257441 Free PMC article.

9

Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D, Finzel BC, Aldrich CC. Bockman MR, et al. Among authors: rhee ky. J Med Chem. 2015 Sep 24;58(18):7349-7369. doi: 10.1021/acs.jmedchem.5b00719. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26299766 Free PMC article.

10

Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase.

Maksymiuk C, Ioerger T, Balakrishnan A, Bryk R, Rhee K, Sacchettini J, Nathan C. Maksymiuk C, et al. Tuberculosis (Edinb). 2015 Dec;95(6):689-694. doi: 10.1016/j.tube.2015.08.009. Epub 2015 Oct 19. Tuberculosis (Edinb). 2015. PMID: 26547230 Free PMC article.

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