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Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.
Chuah MK, Petrus I, De Bleser P, Le Guiner C, Gernoux G, Adjali O, Nair N, Willems J, Evens H, Rincon MY, Matrai J, Di Matteo M, Samara-Kuko E, Yan B, Acosta-Sanchez A, Meliani A, Cherel G, Blouin V, Christophe O, Moullier P, Mingozzi F, VandenDriessche T. Chuah MK, et al. Among authors: petrus i. Mol Ther. 2014 Sep;22(9):1605-13. doi: 10.1038/mt.2014.114. Epub 2014 Jun 23. Mol Ther. 2014. PMID: 24954473 Free PMC article.
Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy.
Vandendriessche T, Thorrez L, Acosta-Sanchez A, Petrus I, Wang L, Ma L, DE Waele L, Iwasaki Y, Gillijns V, Wilson JM, Collen D, Chuah MK. Vandendriessche T, et al. Among authors: petrus i. J Thromb Haemost. 2007 Jan;5(1):16-24. doi: 10.1111/j.1538-7836.2006.02220.x. Epub 2006 Sep 26. J Thromb Haemost. 2007. PMID: 17002653 Free article.
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease.
De Meyer SF, Vandeputte N, Pareyn I, Petrus I, Lenting PJ, Chuah MK, VandenDriessche T, Deckmyn H, Vanhoorelbeke K. De Meyer SF, et al. Among authors: petrus i. Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1621-6. doi: 10.1161/ATVBAHA.108.168369. Epub 2008 Jun 12. Arterioscler Thromb Vasc Biol. 2008. PMID: 18556568 Free article.