Zhen X - Search Results

1

(6aR)-11-amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.

Zhao R, Lu W, Fang X, Guo L, Yang Z, Ye N, Zhao J, Liu Z, Jia J, Zheng L, Zhao B, Zhang A, Zhen X. Zhao R, et al. Among authors: zhen x. Pharmacol Biochem Behav. 2014 Sep;124:204-10. doi: 10.1016/j.pbb.2014.06.011. Epub 2014 Jun 21. Pharmacol Biochem Behav. 2014. PMID: 24955866

2

Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.

Liu Z, Zhang H, Ye N, Zhang J, Wu Q, Sun P, Li L, Zhen X, Zhang A. Liu Z, et al. Among authors: zhen x. J Med Chem. 2010 Feb 11;53(3):1319-28. doi: 10.1021/jm9015763. J Med Chem. 2010. PMID: 20041669

3

Further SAR study on 11-O-substituted aporphine analogues: identification of highly potent dopamine D3 receptor ligands.

Ye N, Wu Q, Zhu L, Zheng L, Gao B, Zhen X, Zhang A. Ye N, et al. Among authors: zhen x. Bioorg Med Chem. 2011 Mar 15;19(6):1999-2008. doi: 10.1016/j.bmc.2011.01.053. Epub 2011 Jan 31. Bioorg Med Chem. 2011. PMID: 21334902

4

Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.

Zhang H, Ye N, Zhou S, Guo L, Zheng L, Liu Z, Gao B, Zhen X, Zhang A. Zhang H, et al. Among authors: zhen x. J Med Chem. 2011 Jul 14;54(13):4324-38. doi: 10.1021/jm200347t. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21591752

5

Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.

Guo L, Chen Y, Zhao R, Wang G, Friedman E, Zhang A, Zhen X. Guo L, et al. Among authors: zhen x. Br J Pharmacol. 2015 Aug;172(16):4052-65. doi: 10.1111/bph.13195. Epub 2015 Jun 26. Br J Pharmacol. 2015. PMID: 25989224 Free PMC article.

6

SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity.

Fang X, Guo L, Jia J, Jin GZ, Zhao B, Zheng YY, Li JQ, Zhang A, Zhen XC. Fang X, et al. Among authors: zhen xc. Acta Pharmacol Sin. 2013 Sep;34(9):1149-55. doi: 10.1038/aps.2013.66. Epub 2013 Jul 29. Acta Pharmacol Sin. 2013. PMID: 23892272 Free PMC article.

7

Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant Activity.

Wang Y, Guo L, Jiang HF, Zheng LT, Zhang A, Zhen XC. Wang Y, et al. CNS Neurosci Ther. 2016 May;22(5):368-77. doi: 10.1111/cns.12502. Epub 2016 Feb 8. CNS Neurosci Ther. 2016. PMID: 26854125 Free PMC article.

8

Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin.

Guo CH, Cao T, Zheng LT, Waddington JL, Zhen XC. Guo CH, et al. Acta Pharmacol Sin. 2020 Apr;41(4):499-507. doi: 10.1038/s41401-020-0379-5. Epub 2020 Feb 28. Acta Pharmacol Sin. 2020. PMID: 32112040 Free PMC article.

9

N-Propylnoraporphin-11-O-yl carboxylic esters as potent dopamine D(2) and serotonin 5-HT(1A) receptor dual ligands.

Liu Z, Chen X, Sun P, Yu L, Zhen X, Zhang A. Liu Z, et al. Among authors: zhen x. Bioorg Med Chem. 2008 Sep 15;16(18):8335-8. doi: 10.1016/j.bmc.2008.08.056. Epub 2008 Aug 28. Bioorg Med Chem. 2008. PMID: 18783955

10

SKF83959 is a potent allosteric modulator of sigma-1 receptor.

Guo L, Zhao J, Jin G, Zhao B, Wang G, Zhang A, Zhen X. Guo L, et al. Among authors: zhen x. Mol Pharmacol. 2013 Mar;83(3):577-86. doi: 10.1124/mol.112.083840. Epub 2013 Jan 7. Mol Pharmacol. 2013. PMID: 23295385

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

932 results

Search Page

Filters