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A gene-driven ENU-based approach to generating an allelic series in any gene.
Quwailid MM, Hugill A, Dear N, Vizor L, Wells S, Horner E, Fuller S, Weedon J, McMath H, Woodman P, Edwards D, Campbell D, Rodger S, Carey J, Roberts A, Glenister P, Lalanne Z, Parkinson N, Coghill EL, McKeone R, Cox S, Willan J, Greenfield A, Keays D, Brady S, Spurr N, Gray I, Hunter J, Brown SD, Cox RD. Quwailid MM, et al. Among authors: wells s. Mamm Genome. 2004 Aug;15(8):585-91. doi: 10.1007/s00335-004-2379-z. Mamm Genome. 2004. PMID: 15457338
Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Warr N, Siggers P, Bogani D, Brixey R, Pastorelli L, Yates L, Dean CH, Wells S, Satoh W, Shimono A, Greenfield A. Warr N, et al. Among authors: wells s. Dev Biol. 2009 Feb 15;326(2):273-84. doi: 10.1016/j.ydbio.2008.11.023. Epub 2008 Dec 7. Dev Biol. 2009. PMID: 19100252 Free article.
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.
Pastorelli LM, Wells S, Fray M, Smith A, Hough T, Harfe BD, McManus MT, Smith L, Woolf AS, Cheeseman M, Greenfield A. Pastorelli LM, et al. Among authors: wells s. Mamm Genome. 2009 Mar;20(3):140-51. doi: 10.1007/s00335-008-9169-y. Epub 2009 Jan 24. Mamm Genome. 2009. PMID: 19169742
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A. Bogani D, et al. Among authors: wells s. PLoS Biol. 2009 Sep;7(9):e1000196. doi: 10.1371/journal.pbio.1000196. Epub 2009 Sep 15. PLoS Biol. 2009. PMID: 19753101 Free PMC article.
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD. Cheeseman MT, et al. Among authors: wells s. PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20. PLoS Genet. 2011. PMID: 22028672 Free PMC article.
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A. Warr N, et al. Among authors: wells s. Dev Cell. 2012 Nov 13;23(5):1020-31. doi: 10.1016/j.devcel.2012.09.016. Epub 2012 Oct 25. Dev Cell. 2012. PMID: 23102580 Free PMC article.
1,780 results