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C. elegans as model for the study of high glucose- mediated life span reduction.
Schlotterer A, Kukudov G, Bozorgmehr F, Hutter H, Du X, Oikonomou D, Ibrahim Y, Pfisterer F, Rabbani N, Thornalley P, Sayed A, Fleming T, Humpert P, Schwenger V, Zeier M, Hamann A, Stern D, Brownlee M, Bierhaus A, Nawroth P, Morcos M. Schlotterer A, et al. Among authors: fleming t. Diabetes. 2009 Nov;58(11):2450-6. doi: 10.2337/db09-0567. Epub 2009 Aug 12. Diabetes. 2009. PMID: 19675139 Free PMC article.
daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans.
Mendler M, Schlotterer A, Ibrahim Y, Kukudov G, Fleming T, Bierhaus A, Riedinger C, Schwenger V, Herzig S, Hecker M, Tyedmers J, Nawroth PP, Morcos M. Mendler M, et al. Among authors: fleming t. Diabetologia. 2015 Feb;58(2):393-401. doi: 10.1007/s00125-014-3415-5. Epub 2014 Oct 17. Diabetologia. 2015. PMID: 25322843
Dicarbonyl Stress Mimics Diabetic Neurovascular Damage in the Retina.
Kolibabka M, Friedrichs P, Dietrich N, Fleming T, Schlotterer A, Hammes HP. Kolibabka M, et al. Among authors: fleming t. Exp Clin Endocrinol Diabetes. 2016 Jul;124(7):437-9. doi: 10.1055/s-0042-106081. Epub 2016 May 24. Exp Clin Endocrinol Diabetes. 2016. PMID: 27219890 Review.
The DPP4 Inhibitor Linagliptin Protects from Experimental Diabetic Retinopathy.
Dietrich N, Kolibabka M, Busch S, Bugert P, Kaiser U, Lin J, Fleming T, Morcos M, Klein T, Schlotterer A, Hammes HP. Dietrich N, et al. Among authors: fleming t. PLoS One. 2016 Dec 12;11(12):e0167853. doi: 10.1371/journal.pone.0167853. eCollection 2016. PLoS One. 2016. PMID: 27942008 Free PMC article.
A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage.
Niopek K, Üstünel BE, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail AM, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes HP, Nawroth P, Fleming T, Conkright MD, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M. Niopek K, et al. Among authors: fleming t. Cell Rep. 2017 Aug 8;20(6):1422-1434. doi: 10.1016/j.celrep.2017.07.023. Cell Rep. 2017. PMID: 28793265 Free article.
1,169 results