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Page 1
Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases.
Petrassi M, Barber R, Be C, Beach S, Cox B, D'Souza AM, Duggan N, Hussey M, Fox R, Hunt P, Jarai G, Kosaka T, Oakley P, Patel V, Press N, Rowlands D, Scheufler C, Schmidt O, Srinivas H, Turner M, Turner R, Westwick J, Wolfreys A, Pathan N, Watson S, Thomas M. Petrassi M, et al. Among authors: oakley p. Front Pharmacol. 2017 May 5;8:240. doi: 10.3389/fphar.2017.00240. eCollection 2017. Front Pharmacol. 2017. PMID: 28529483 Free PMC article.
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.
Churcher I, Beher D, Best JD, Castro JL, Clarke EE, Gentry A, Harrison T, Hitzel L, Kay E, Kerrad S, Lewis HD, Morentin-Gutierrez P, Mortishire-Smith R, Oakley PJ, Reilly M, Shaw DE, Shearman MS, Teall MR, Williams S, Wrigley JD. Churcher I, et al. Among authors: oakley pj. Bioorg Med Chem Lett. 2006 Jan 15;16(2):280-4. doi: 10.1016/j.bmcl.2005.10.009. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275079
Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
Cole AG, Metzger A, Brescia MR, Qin LY, Appell KC, Brain CT, Hallett A, Ganju P, Denholm AA, Wareing JR, Ritchie TJ, Drake GM, Bevan SJ, MacGloinn A, McBryde A, Patel V, Oakley PJ, Nunez X, Gstach H, Schneider P, Baldwin JJ, Dolle RE, McDonald E, Henderson I. Cole AG, et al. Among authors: oakley pj. Bioorg Med Chem Lett. 2009 Jan 1;19(1):119-22. doi: 10.1016/j.bmcl.2008.11.005. Epub 2008 Nov 6. Bioorg Med Chem Lett. 2009. PMID: 19014884
Aryl sulfones: a new class of gamma-secretase inhibitors.
Teall M, Oakley P, Harrison T, Shaw D, Kay E, Elliott J, Gerhard U, Castro JL, Shearman M, Ball RG, Tsou NN. Teall M, et al. Among authors: oakley p. Bioorg Med Chem Lett. 2005 May 16;15(10):2685-8. doi: 10.1016/j.bmcl.2004.12.017. Bioorg Med Chem Lett. 2005. PMID: 15863342
Prediction of retention for sulfonamides in supercritical fluid chromatography.
Cazenave-Gassiot A, Boughtflower R, Caldwell J, Coxhead R, Hitzel L, Lane S, Oakley P, Holyoak C, Pullen F, Langley GJ. Cazenave-Gassiot A, et al. Among authors: oakley p. J Chromatogr A. 2008 May 2;1189(1-2):254-65. doi: 10.1016/j.chroma.2007.10.020. Epub 2007 Oct 12. J Chromatogr A. 2008. PMID: 17977551
Lumbar spine coronal balance parameters as a predictor of rehabilitation management outcomes in patients with radiculopathy due to lumbar disc herniation: A multicenter prospective case series study.
Aljallad YA, Moustafa IM, Badr M, Hamza N, Oakley PA, Harrison DE. Aljallad YA, et al. Among authors: oakley pa. Heliyon. 2024 Nov 23;10(23):e40613. doi: 10.1016/j.heliyon.2024.e40613. eCollection 2024 Dec 15. Heliyon. 2024. PMID: 39669154 Free PMC article.
172 results