Kalyuzhny AE - Search Results

1

Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects.

Le Naour M, Lunzer MM, Powers MD, Kalyuzhny AE, Benneyworth MA, Thomas MJ, Portoghese PS. Le Naour M, et al. Among authors: kalyuzhny ae. J Med Chem. 2014 Aug 14;57(15):6383-92. doi: 10.1021/jm500159d. Epub 2014 Jul 18. J Med Chem. 2014. PMID: 24978316 Free PMC article.

2

N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers.

Yekkirala AS, Lunzer MM, McCurdy CR, Powers MD, Kalyuzhny AE, Roerig SC, Portoghese PS. Yekkirala AS, et al. Among authors: kalyuzhny ae. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5098-103. doi: 10.1073/pnas.1016277108. Epub 2011 Mar 8. Proc Natl Acad Sci U S A. 2011. PMID: 21385944 Free PMC article.

3

An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands.

Yekkirala AS, Kalyuzhny AE, Portoghese PS. Yekkirala AS, et al. Among authors: kalyuzhny ae. ACS Chem Biol. 2013 Jul 19;8(7):1412-6. doi: 10.1021/cb400113d. Epub 2013 May 17. ACS Chem Biol. 2013. PMID: 23675763 Free PMC article.

4

Bivalent ligands that target μ opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance.

Le Naour M, Akgün E, Yekkirala A, Lunzer MM, Powers MD, Kalyuzhny AE, Portoghese PS. Le Naour M, et al. Among authors: kalyuzhny ae. J Med Chem. 2013 Jul 11;56(13):5505-13. doi: 10.1021/jm4005219. Epub 2013 Jun 20. J Med Chem. 2013. PMID: 23734559 Free PMC article.

5

The bivalent ligand, MMG22, reduces neuropathic pain after nerve injury without the side effects of traditional opioids.

Speltz R, Lunzer MM, Shueb SS, Akgün E, Reed R, Kalyuzhny A, Portoghese PS, Simone DA. Speltz R, et al. Pain. 2020 Sep 1;161(9):2041-2057. doi: 10.1097/j.pain.0000000000001902. Pain. 2020. PMID: 32345918 Free PMC article.

6

Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists.

Yekkirala AS, Kalyuzhny AE, Portoghese PS. Yekkirala AS, et al. Among authors: kalyuzhny ae. ACS Chem Neurosci. 2010 Feb 17;1(2):146-54. doi: 10.1021/cn9000236. Epub 2009 Nov 25. ACS Chem Neurosci. 2010. PMID: 22816017 Free PMC article.

7

Immunohistochemical localization of mu-, delta- and kappa-opioid receptors within the antinociceptive brainstem circuits.

Kalyuzhny AE. Kalyuzhny AE. Methods Mol Med. 2003;84:79-93. doi: 10.1385/1-59259-379-8:79. Methods Mol Med. 2003. PMID: 12703319 No abstract available.

8

mu-Opioid and delta-opioid receptors are expressed in brainstem antinociceptive circuits: studies using immunocytochemistry and retrograde tract-tracing.

Kalyuzhny AE, Arvidsson U, Wu W, Wessendorf MW. Kalyuzhny AE, et al. J Neurosci. 1996 Oct 15;16(20):6490-503. doi: 10.1523/JNEUROSCI.16-20-06490.1996. J Neurosci. 1996. PMID: 8815927 Free PMC article.

9

Serotonergic and GABAergic neurons in the medial rostral ventral medulla express kappa-opioid receptor immunoreactivity.

Kalyuzhny AE, Wessendorf MW. Kalyuzhny AE, et al. Neuroscience. 1999 Apr;90(1):229-34. doi: 10.1016/s0306-4522(98)00376-5. Neuroscience. 1999. PMID: 10188949

10

Opioid- and GABA(A)-receptors are co-expressed by neurons in rat brain.

Kalyuzhny AE, Dooyema J, Wessendorf MW. Kalyuzhny AE, et al. Neuroreport. 2000 Aug 21;11(12):2625-8. doi: 10.1097/00001756-200008210-00004. Neuroreport. 2000. PMID: 10976932

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