Lunzer MM - Search Results

1

Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects.

Le Naour M, Lunzer MM, Powers MD, Kalyuzhny AE, Benneyworth MA, Thomas MJ, Portoghese PS. Le Naour M, et al. Among authors: lunzer mm. J Med Chem. 2014 Aug 14;57(15):6383-92. doi: 10.1021/jm500159d. Epub 2014 Jul 18. J Med Chem. 2014. PMID: 24978316 Free PMC article.

2

Reporter affinity labels: an o-phthalaldehyde derivative of beta-naltrexamine as a fluorogenic ligand for opioid receptors.

Le Bourdonnec B, El Kouhen R, Lunzer MM, Law PY, Loh HH, Portoghese PS. Le Bourdonnec B, et al. Among authors: lunzer mm. J Med Chem. 2000 Jun 29;43(13):2489-92. doi: 10.1021/jm000138s. J Med Chem. 2000. PMID: 10891107 No abstract available.

3

Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.

Portoghese PS, Lunzer MM. Portoghese PS, et al. Among authors: lunzer mm. Eur J Pharmacol. 2003 Apr 25;467(1-3):233-4. doi: 10.1016/s0014-2999(03)01599-1. Eur J Pharmacol. 2003. PMID: 12706480

4

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL. Waldhoer M, et al. Among authors: lunzer mm. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):9050-5. doi: 10.1073/pnas.0501112102. Epub 2005 Jun 2. Proc Natl Acad Sci U S A. 2005. PMID: 15932946 Free PMC article.

5

Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia.

Lunzer MM, Yekkirala A, Hebbel RP, Portoghese PS. Lunzer MM, et al. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6061-5. doi: 10.1073/pnas.0700295104. Epub 2007 Mar 26. Proc Natl Acad Sci U S A. 2007. PMID: 17389363 Free PMC article.

6

Selectivity of delta- and kappa-opioid ligands depends on the route of central administration in mice.

Lunzer MM, Portoghese PS. Lunzer MM, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):166-71. doi: 10.1124/jpet.107.120279. Epub 2007 Mar 30. J Pharmacol Exp Ther. 2007. PMID: 17400888

7

Induced association of mu opioid (MOP) and type 2 cholecystokinin (CCK2) receptors by novel bivalent ligands.

Zheng Y, Akgün E, Harikumar KG, Hopson J, Powers MD, Lunzer MM, Miller LJ, Portoghese PS. Zheng Y, et al. Among authors: lunzer mm. J Med Chem. 2009 Jan 22;52(2):247-58. doi: 10.1021/jm800174p. J Med Chem. 2009. PMID: 19113864 Free PMC article.

8

N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers.

Yekkirala AS, Lunzer MM, McCurdy CR, Powers MD, Kalyuzhny AE, Roerig SC, Portoghese PS. Yekkirala AS, et al. Among authors: lunzer mm. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5098-103. doi: 10.1073/pnas.1016277108. Epub 2011 Mar 8. Proc Natl Acad Sci U S A. 2011. PMID: 21385944 Free PMC article.

9

Opioid activity of spinally selective analogues of N-naphthoyl-β-naltrexamine in HEK-293 cells and mice.

Le Naour M, Lunzer MM, Powers MD, Portoghese PS. Le Naour M, et al. Among authors: lunzer mm. J Med Chem. 2012 Jan 26;55(2):670-7. doi: 10.1021/jm200902v. Epub 2012 Jan 5. J Med Chem. 2012. PMID: 22136373 Free PMC article.

10

Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys.

Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Yekkirala AS, et al. Among authors: lunzer mm. ACS Chem Neurosci. 2012 Sep 19;3(9):720-7. doi: 10.1021/cn300049m. Epub 2012 Jul 5. ACS Chem Neurosci. 2012. PMID: 23019498 Free PMC article.

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