Humbert N - Search Results

1

Functional and structural characterization of 2-amino-4-phenylthiazole inhibitors of the HIV-1 nucleocapsid protein with antiviral activity.

Mori M, Nucci A, Lang MC, Humbert N, Boudier C, Debaene F, Sanglier-Cianferani S, Catala M, Schult-Dietrich P, Dietrich U, Tisné C, Mely Y, Botta M. Mori M, et al. Among authors: humbert n. ACS Chem Biol. 2014 Sep 19;9(9):1950-5. doi: 10.1021/cb500316h. Epub 2014 Jul 7. ACS Chem Biol. 2014. PMID: 24988251

2

Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein.

Mori M, Schult-Dietrich P, Szafarowicz B, Humbert N, Debaene F, Sanglier-Cianferani S, Dietrich U, Mély Y, Botta M. Mori M, et al. Among authors: humbert n. Virus Res. 2012 Nov;169(2):377-87. doi: 10.1016/j.virusres.2012.05.011. Epub 2012 May 24. Virus Res. 2012. PMID: 22634301 Review.

3

Comparative nucleic acid chaperone properties of the nucleocapsid protein NCp7 and Tat protein of HIV-1.

Godet J, Boudier C, Humbert N, Ivanyi-Nagy R, Darlix JL, Mély Y. Godet J, et al. Among authors: humbert n. Virus Res. 2012 Nov;169(2):349-60. doi: 10.1016/j.virusres.2012.06.021. Epub 2012 Jun 26. Virus Res. 2012. PMID: 22743066 Free PMC article. Review.

4

A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions.

Vercruysse T, Basta B, Dehaen W, Humbert N, Balzarini J, Debaene F, Sanglier-Cianférani S, Pannecouque C, Mély Y, Daelemans D. Vercruysse T, et al. Among authors: humbert n. Retrovirology. 2012 Nov 12;9:95. doi: 10.1186/1742-4690-9-95. Retrovirology. 2012. PMID: 23146561 Free PMC article.

5

Dynamic interactions of the HIV-1 Tat with nucleic acids are critical for Tat activity in reverse transcription.

Boudier C, Humbert N, Chaminade F, Chen Y, de Rocquigny H, Godet J, Mauffret O, Fossé P, Mély Y. Boudier C, et al. Among authors: humbert n. Nucleic Acids Res. 2014 Jan;42(2):1065-78. doi: 10.1093/nar/gkt934. Epub 2013 Oct 22. Nucleic Acids Res. 2014. PMID: 24153111 Free PMC article.

6

Fully regiocontrolled polyarylation of pyridine.

Doebelin C, Wagner P, Bihel F, Humbert N, Kenfack CA, Mely Y, Bourguignon JJ, Schmitt M. Doebelin C, et al. Among authors: humbert n. J Org Chem. 2014 Feb 7;79(3):908-18. doi: 10.1021/jo402200q. Epub 2014 Jan 22. J Org Chem. 2014. PMID: 24417295

7

A Toolbox of Chromones and Quinolones for Measuring a Wide Range of ATP Concentrations.

Pivovarenko VG, Bugera O, Humbert N, Klymchenko AS, Mély Y. Pivovarenko VG, et al. Among authors: humbert n. Chemistry. 2017 Sep 4;23(49):11927-11934. doi: 10.1002/chem.201702484. Epub 2017 Aug 9. Chemistry. 2017. PMID: 28708306

8

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.

Mori M, Kovalenko L, Malancona S, Saladini F, De Forni D, Pires M, Humbert N, Real E, Botzanowski T, Cianférani S, Giannini A, Dasso Lang MC, Cugia G, Poddesu B, Lori F, Zazzi M, Harper S, Summa V, Mely Y, Botta M. Mori M, et al. Among authors: humbert n. ACS Chem Biol. 2018 Jan 19;13(1):253-266. doi: 10.1021/acschembio.7b00907. Epub 2017 Dec 28. ACS Chem Biol. 2018. PMID: 29235845

9

Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein.

Shvadchak V, Zgheib S, Basta B, Humbert N, Langedijk J, Morris MC, Ciaco S, Maskri O, Darlix JL, Mauffret O, Fossé P, Réal E, Mély Y. Shvadchak V, et al. Among authors: humbert n. Biochemistry. 2018 Jul 31;57(30):4562-4573. doi: 10.1021/acs.biochem.8b00527. Epub 2018 Jul 18. Biochemistry. 2018. PMID: 30019894

10

Annealing of ssDNA and compaction of dsDNA by the HIV-1 nucleocapsid and Gag proteins visualized using nanofluidic channels.

Jiang K, Humbert N, Kk S, Lequeu T, Lin YL, Mely Y, Westerlund F. Jiang K, et al. Among authors: humbert n. Q Rev Biophys. 2019 Jan;52:e2. doi: 10.1017/S0033583518000124. Q Rev Biophys. 2019. PMID: 30912495

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