Iizuka A - Search Results

1

One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice.

Saida H, Matsuzaki Y, Takayama K, Iizuka A, Konno A, Yanagi S, Hirai H. Saida H, et al. Among authors: iizuka a. Gene Ther. 2014 Sep;21(9):820-7. doi: 10.1038/gt.2014.60. Epub 2014 Jul 3. Gene Ther. 2014. PMID: 24989813

2

Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.

Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H. Torashima T, et al. Among authors: iizuka a. EMBO Rep. 2008 Apr;9(4):393-9. doi: 10.1038/embor.2008.31. Epub 2008 Mar 14. EMBO Rep. 2008. PMID: 18344973 Free PMC article.

3

High transgene expression by lentiviral vectors causes maldevelopment of Purkinje cells in vivo.

Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev AN, Koyama C, Hirai H. Sawada Y, et al. Among authors: iizuka a. Cerebellum. 2010 Sep;9(3):291-302. doi: 10.1007/s12311-010-0161-1. Cerebellum. 2010. PMID: 20178014

4

Lentiviral vector-mediated rescue of motor behavior in spontaneously occurring hereditary ataxic mice.

Iizuka A, Takayama K, Torashima T, Yamasaki M, Koyama C, Mitsumura K, Watanabe M, Hirai H. Iizuka A, et al. Neurobiol Dis. 2009 Sep;35(3):457-65. doi: 10.1016/j.nbd.2009.06.007. Epub 2009 Jun 30. Neurobiol Dis. 2009. PMID: 19573599

5

Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar Purkinje cells.

Konno A, Shuvaev AN, Miyake N, Miyake K, Iizuka A, Matsuura S, Huda F, Nakamura K, Yanagi S, Shimada T, Hirai H. Konno A, et al. Among authors: iizuka a. Cerebellum. 2014 Feb;13(1):29-41. doi: 10.1007/s12311-013-0516-5. Cerebellum. 2014. PMID: 23955261

6

Mesenchymal stem cells ameliorate cerebellar pathology in a mouse model of spinocerebellar ataxia type 1.

Matsuura S, Shuvaev AN, Iizuka A, Nakamura K, Hirai H. Matsuura S, et al. Among authors: iizuka a. Cerebellum. 2014 Jun;13(3):323-30. doi: 10.1007/s12311-013-0536-1. Cerebellum. 2014. PMID: 24242763

7

Long-term oral administration of the NMDA receptor antagonist memantine extends life span in spinocerebellar ataxia type 1 knock-in mice.

Iizuka A, Nakamura K, Hirai H. Iizuka A, et al. Neurosci Lett. 2015 Apr 10;592:37-41. doi: 10.1016/j.neulet.2015.02.055. Epub 2015 Feb 25. Neurosci Lett. 2015. PMID: 25725171

8

Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα.

Iizuka A, Matsuzaki Y, Konno A, Hirai H. Iizuka A, et al. Brain Struct Funct. 2016 Jul;221(6):2879-89. doi: 10.1007/s00429-015-1077-9. Epub 2015 Jun 30. Brain Struct Funct. 2016. PMID: 26122696

9

Morphological and Functional Attenuation of Degeneration of Peripheral Neurons by Mesenchymal Stem Cell-Conditioned Medium in Spinocerebellar Ataxia Type 1-Knock-in Mice.

Suto N, Mieda T, Iizuka A, Nakamura K, Hirai H. Suto N, et al. Among authors: iizuka a. CNS Neurosci Ther. 2016 Aug;22(8):670-6. doi: 10.1111/cns.12560. Epub 2016 May 3. CNS Neurosci Ther. 2016. PMID: 27140210 Free PMC article.

10

Mutant PKCγ in spinocerebellar ataxia type 14 disrupts synapse elimination and long-term depression in Purkinje cells in vivo.

Shuvaev AN, Horiuchi H, Seki T, Goenawan H, Irie T, Iizuka A, Sakai N, Hirai H. Shuvaev AN, et al. Among authors: iizuka a. J Neurosci. 2011 Oct 5;31(40):14324-34. doi: 10.1523/JNEUROSCI.5530-10.2011. J Neurosci. 2011. PMID: 21976518 Free PMC article.

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