Clarke AR - Search Results

1

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked.

Sandberg MK, Al-Doujaily H, Sharps B, De Oliveira MW, Schmidt C, Richard-Londt A, Lyall S, Linehan JM, Brandner S, Wadsworth JD, Clarke AR, Collinge J. Sandberg MK, et al. Among authors: clarke ar. Nat Commun. 2014 Jul 9;5:4347. doi: 10.1038/ncomms5347. Nat Commun. 2014. PMID: 25005024 Free PMC article.

2

Inhibition of proteinase K activity by copper(II) ions.

Stone LA, Jackson GS, Collinge J, Wadsworth JD, Clarke AR. Stone LA, et al. Among authors: clarke ar. Biochemistry. 2007 Jan 9;46(1):245-52. doi: 10.1021/bi061646s. Biochemistry. 2007. PMID: 17198395

3

A general model of prion strains and their pathogenicity.

Collinge J, Clarke AR. Collinge J, et al. Among authors: clarke ar. Science. 2007 Nov 9;318(5852):930-6. doi: 10.1126/science.1138718. Science. 2007. PMID: 17991853 Review.

4

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases.

Sandberg MK, Al-Doujaily H, Sharps B, Clarke AR, Collinge J. Sandberg MK, et al. Among authors: clarke ar. Nature. 2011 Feb 24;470(7335):540-2. doi: 10.1038/nature09768. Nature. 2011. PMID: 21350487

5

N-terminal domain of prion protein directs its oligomeric association.

Trevitt CR, Hosszu LL, Batchelor M, Panico S, Terry C, Nicoll AJ, Risse E, Taylor WA, Sandberg MK, Al-Doujaily H, Linehan JM, Saibil HR, Scott DJ, Collinge J, Waltho JP, Clarke AR. Trevitt CR, et al. Among authors: clarke ar. J Biol Chem. 2014 Sep 12;289(37):25497-508. doi: 10.1074/jbc.M114.566588. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074940 Free PMC article.

6

A systematic investigation of production of synthetic prions from recombinant prion protein.

Schmidt C, Fizet J, Properzi F, Batchelor M, Sandberg MK, Edgeworth JA, Afran L, Ho S, Badhan A, Klier S, Linehan JM, Brandner S, Hosszu LL, Tattum MH, Jat P, Clarke AR, Klöhn PC, Wadsworth JD, Jackson GS, Collinge J. Schmidt C, et al. Among authors: clarke ar. Open Biol. 2015 Dec;5(12):150165. doi: 10.1098/rsob.150165. Open Biol. 2015. PMID: 26631378 Free PMC article.

7

Strain-specific prion-protein conformation determined by metal ions.

Wadsworth JD, Hill AF, Joiner S, Jackson GS, Clarke AR, Collinge J. Wadsworth JD, et al. Among authors: clarke ar. Nat Cell Biol. 1999 May;1(1):55-9. doi: 10.1038/9030. Nat Cell Biol. 1999. PMID: 10559865

8

Removal of the glycosylphosphatidylinositol anchor from PrP(Sc) by cathepsin D does not reduce prion infectivity.

Lewis PA, Properzi F, Prodromidou K, Clarke AR, Collinge J, Jackson GS. Lewis PA, et al. Among authors: clarke ar. Biochem J. 2006 Apr 15;395(2):443-8. doi: 10.1042/BJ20051677. Biochem J. 2006. PMID: 16441239 Free PMC article.

9

Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.

Khalili-Shirazi A, Kaisar M, Mallinson G, Jones S, Bhelt D, Fraser C, Clarke AR, Hawke SH, Jackson GS, Collinge J. Khalili-Shirazi A, et al. Among authors: clarke ar. Biochim Biophys Acta. 2007 Nov;1774(11):1438-50. doi: 10.1016/j.bbapap.2007.08.028. Epub 2007 Sep 6. Biochim Biophys Acta. 2007. PMID: 17936697

10

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.

Cronier S, Gros N, Tattum MH, Jackson GS, Clarke AR, Collinge J, Wadsworth JD. Cronier S, et al. Among authors: clarke ar. Biochem J. 2008 Dec 1;416(2):297-305. doi: 10.1042/BJ20081235. Biochem J. 2008. PMID: 18684106 Free PMC article.

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